نتایج جستجو برای: rs11614913

تعداد نتایج: 136  

Micro-RNAs are a large group of non-coding RNAs of 18-25 nucleotides in length. Polymorphisms in the human pre-mir-RNAs could change the efficiency of target cell and can also play a role in cell cycle regulation and cancer. The aim of this study is to investigate the association of rs11614913 T/C polymorphism with gastric cancer risk in Ardabil Province. In a case-control study, this polymorph...

2016
Ming Chen Fukang Luo Juanchun Yu Guiming Xiang Dongneng Jiang Xiaoyun Pu

BACKGROUND Mutations or single nucleotide polymorphisms (SNPs) within the gene region of microRNAs play an important role for the development of hepatocellular carcinoma (HCC). Extensive studies have tried to investigate the susceptibility role of miR-146a rs2819164 and miR-196a-2 rs11614913. However, these results are still inconsistent and inconclusive. We undertook a meta-analysis containing...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2013
L Stenholm J Stoehlmacher-Williams S E Al-Batran N Heussen S Akin C Pauligk S Lehmann T Senff R D Hofheinz G Ehninger M Kramer E Goekkurt

BACKGROUND To determine the prognostic role of selected microRNA (miRNA) polymorphisms in advanced gastric cancer (AGC). PATIENTS AND METHODS Six hundred and seventy-four AGC patients received 5-fluorouracil (F), leucovorin (L), oxaliplatin (O) or FL + cisplatin (P) or additional docetaxel (T) to FLO (FLOT) within four clinical trials. Polymorphisms of mir-26a1 (rs7372209), mir-27a (rs895819)...

Journal: :journal of genetic resources 0
mahshid damandan genetics graduate student at islamic azad university of ahar, iran rouhollah moradpour hesari department of genetic imam hospital, ardabil university of medical sciences, ardabil, islamic republic of iran

micro-rnas are a large group of non-coding rnas with 18-25 nucleotides. polymorphisms in the human pre-mir-rna could change the efficiency of target cell and can also play a role in cell cycle regulation and cancer. the aim of this study was to investigate the association of rs11614913 t/c polymorphism with gastric cancer risk in ardabil province. in a case-control study, this polymorphism was ...

2015
Suli Huang Shiquan Zhou Yanwei Zhang Ziquan Lv Shanshan Li Changhui Xie Yuebin Ke Pingjian Deng Yijie Geng Qian Zhang Xiaofan Chu Zhaohui Yi Ying Zhang Tangchun Wu Jinquan Cheng

microRNA (miRNA) plays a role in the pathogenesis of ischemic stroke, and single nucleotide polymorphisms in miRNA genes may contribute to disease susceptibility. However, the effect of miR-146a, miR-196a2, and miR-499 polymorphisms on ischemic stroke susceptibility has been rarely reported. Using the TaqMan assay, we evaluated the association of hsa-miR-146a/rs2910164, hsa-miR-196a2/rs11614913...

2016
Chengyuan Wang Erich M. Sturgis Xingming Chen Hongliang Zheng Qingyi Wei Guojun Li

Functional polymorphisms of miRNAs may affect the function and target expression of miRNAs, which can, in turn, affect the biological activity, etiology, and prognosis of cancer. We hypothesized that four common polymorphisms in pre-miRNAs (hsa-mir-146a rs2910164 G > C, hsa-mir-196a2 rs11614913 C > T, hsa-mir-149 rs2292832 G > T, and hsa-mir-499 rs3746444 A > G) are associated with survival in ...

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