This study evaluated the possible protective effect of Crocus sativus L. (saffron) in the treatment of renal calculi. Aqueous extract of saffron (25, 50 and 100 mg/kg, daily) was administered intraperitoneally in two regimens of protective or curative, using male Wistar rats. Urolithiasis was induced by ethylene glycol (% 0.75) in drinking water. Urine was collected for biochemical analysis and...

Saffron, the dried red-orange stigmas of Crocus sativus L, has been known as a flavoring agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. These components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...

Crocus ancyrensis is a yellow-flowered species and in the same family genus with saffron. Although various studies have been conducted on antioxidant capacity essential oil content characterization of saffron (Crocus sativus), there no literature information about C. plant, which known as among people. The members contain many valuable components including antioxidants, phenolic compounds oils....

Crocin( Crocetin di-gentiobiose ester ) is the chemical constituent isolated from the Saffron, the dried trifid stigma of the plant Crocus sativus L. and also from the fruits of Gardenia(Gardenia jasminoides Ellis) It is found to be effective as antiproliferative, anti-oxidant, learning and memory enhancer, brain neurodegenerative disorder, sperm cryoconservation, biosurfactant, alzheimer disor...

BACKGROUND The cultivation of saffron is expanding through the southeast of Iran, and allergy to saffron pollen occurs in workers involved in processing this plant. We aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. METHODS The N-terminal amino acid sequence of Cro s 1, an allergen from saffron...

Crocus sativus, known as saffron, is used in folk medicine for treatment of different types of diseases, and its anti-inflammatory and free radical scavenging activities have been demonstrated. The present study evaluated gentamicin nephrotoxicity in saffron treated rats. Male Wistar rats (200-250 g) were treated with saffron (40 or 80 mg/k/d) for 10 days, or saffron (40 or 80 mg/ kg/d) for 10 ...

Saffron (Crocus sativus L.) is a light purple flower with reddish colored stigma. It is one of the most expensive spices with a range of quality in its color and aroma. A few key countries involved in saffron commercialization are Spain, Iran, Greece, Morocco, India and China. The main chemical constituents found in saffron are safranal, picrocrocin, crocetin and its glycoside, crocins. These c...

OBJECTIVES Recently, a great deal of interest has been developed to isolate and investigate novel bioactive components from natural resources with health beneficial effects. Saffron is the dried stigma of Crocus sativus L. and has been used for centuries in traditional medicine mainly for its healing properties, as well as for the treatment of various pathological conditions. Objectives of the ...

Non-alcoholic fatty liver disease (NAFLD) is the result of the accumulation of adipose tissue deposits in the liver and it is associated with type 2 diabetes. Crocus sativus (saffron) is known for its antioxidant and its potential hypoglycemic effects. We investigated the role of saffron on NAFLD in diabetic rats. Thirty adult male rats were allocated into three groups; control (n=10), which re...