acinic cell carcinoma arising in salivary glands is a rare tumor, accounting for 2% to 5% of the primary neoplasms of the parotid gland. when these tumors are well-differentiated, the neoplasia has innocuous aspect, due to the similarity to normal parotid tissue. this makes the diagnosis difficult. initially the malignancy of this tumor was uncertain; however, recent studies have declared it as...

Sialodochitis fibrinosa (or commonly known as Kussmaul Disease) is a rare salivary gland disease characterized by recurrent salivary gland swelling and pain as a result of mucofibrinous plugs. Typically patients have a history of multiply recurrent glandular swelling, dehydration and/or decreased salivary flow, thick secretions from Stensen's or Wharton's duct, and/or history of allergic diseas...

background and aims. various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. experimental results support the hypothesis that increased crkii proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. the aim of this study was to assess t...

Introduction: Cyfra 21 is a serum-soluble fragment of cytokeratin19. Increased Cyfra 21 serum levels and their benefit as a tumor marker have been shown in some malignancies. This study aimed to evaluate the serum levels of Cyfra 21 in patients with benign and malignant salivary gland tumors. Materials and Methods: In this cross-sectional study, the serum level of Cyfra 21 in 44 patients with m...

Sialolithiasis is a common disorder affecting an estimated 12 in 1000 people each year and it accounts for more than fifty percent of the salivary gland diseases [1]. Although it can be found in children, it more commonly affects adults in their third to sixth decades [2]. There is a male predominance in sialoliths with some authors quoting that over 80% of the salivary calculi occur in the sub...

Background and objective: Fine needle aspiration cytology (FNAC) of salivary gland lesions is an accepted and useful diagnostic tool to differentiate between benign and malignant lesions. Majority of the neoplasms are benign, and specific diagnosis on cytology can be made in most of the cases. However, the utility is limited by the overlapping and heterogeneous morphol...

conclusions the agnor technique can be used to diagnose salivary gland tumors. results the chi-square test showed significant differences between tumor types and the numbers of agnors (p = 0.000) and between tumor types and areas of agnors (p = 0.000). objectives the purpose of this study was to determine the numbers and mean areas of the agnor dots in the 3 most common salivary gland tumors. m...

BACKGROUND Early studies suggested that salivary gland dysfunction was a normal sequela of aging. Recent research on healthy, different-aged adults has led to a revision of these former conclusions. Parotid gland function appears to be age-stable, yet there is no consensus on submandibular/sublingual output. To date, there have only been two longitudinal studies utilizing healthy individuals ex...

Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

............................................................................................................. v List of Tables ..................................................................................................... ix List of Figures ..................................................................................................... x Chapter 1: Introduction ........................