The purpose of the present study was to evaluate the validity of a scoring system based on excretion rate of salivary gland scintigraphy in patients with Sjögren's syndrome (SjS). Total scintigraphic scores were compared with the results of the Saxon test. One hundred and twenty-four subjects who were clinically diagnosed with SjS and 11 normal ones underwent salivary gland scintigraphy and the...

background: salivary gland tumors are among malignancies that have high recurrence rate. immune responses in salivary gland tumors have not been well elucidated. t helper type 1 (th1) and th2 cytokines have been reported to play a role in the outcome of head and neck cancers. objective: to evaluate the serum levels of interferon gamma (ifn- γ), as the hallmark of th1 cytokines, and interleukin-...

Introduction: Chronic sclerosing sialadenitis is a relatively uncommon disorder of the salivary gland. Because of its clinical similarity to a salivary gland neoplasm, this condition has been known as Kuttner tumor and is classified as a tumorlike lesion. Case Report: This is the first reported case of bilateral Kuttner tumor of the submandibular glands in Iran. It was initially diagnosed as...

PURPOSE One of the major reasons for failure of radiotherapeutic cancer treatment is the limitation in dose that can be applied to the tumor because of coirradiation of the normal healthy tissue. Late radiation-induced damage reduces the quality of life of the patient and may even be life threatening. Replacement of the radiation-sterilized stem cells with unirradiated autologous stem cells may...

The exposure to high doses of ionizing radiation during radiotherapy results in severe morphological and functional alterations of the salivary glands, such as xerostomia. In the present study we investigated the chronic effect of a single radiation dose of 15 Gray (Gy) limited to head and neck on rat salivary gland function (salivary secretion and gland mass) and histology. Results indicate th...

The Drosophila embryonic salivary gland is formed by the invagination and collective migration of cells. Here, we report on a novel developmental role for receptor-type guanylyl cyclase at 76C, Gyc76C, in morphogenesis of the salivary gland. We demonstrate that Gyc76C and downstream cGMP-dependent protein kinase 1 (DG1) function in the gland and surrounding mesoderm to control invagination, col...

Salivary glands are important for secretion of saliva, which is essential for bolus formation, swallowing and maintaining a healthy oral cavity [1]. Salivary glands consist of acinar and duct cells. Injury to salivary glands, such as the damage that occurs following radiation treatment for head and neck cancer, causes a decrease in the number of acinar cells and the ability of the glands to pro...

the gross and microscopic anatomy of the molar salivary gland of the domestic cat was studied. in this research, five pair of molar glandsfrom five male adult cats were used. in cat, the molar gland was elongated rectangle shape and was located obliquely in the submucosal fossa of the inferior lip, near the oral commissure. the dorsal border of the molar gland was attached to the masseter muscl...

major salivary gland tumors are uncommon and the exact nature of these tumors is not obvious. this study was carried out to compare the histological results of intraoperative frozen sections against those of permanent reports for major salivary glands masses. one hundred thirty-nine patients with major salivary gland masses who were candidates for surgery underwent an intraoperative frozen sect...