Background: Osteoporosis is related to the decrease of bone density, osteoporosis requires attention from dentists because it can also occurs in the jaw bone. Osteoporosis is calculated with a quantitative assessment of bone density, which is called Bone Mineral Density (BMD). The best imaging modalities to assess bone density are the Dual Energy examination methods X-ray Absorptiometry (DEXA)....

The osteoblast-derived hormone osteocalcin promotes testosterone biosynthesis in the mouse testis by binding to GPRC6A in Leydig cells. Interestingly, Osteocalcin-deficient mice exhibit increased levels of luteinizing hormone (LH), a pituitary hormone that regulates sex steroid synthesis in the testes. These observations raise the question of whether LH regulates osteocalcin's reproductive effe...

introduction sialolithiasis is the most common disease of salivary glands. sialography is particularly important for the assessment of the outflow tract and in diagnosing obstructive salivary gland lesions including calculi. case presentation we report on a 38-year-old female with sialolithiasis whom had wharton’s duct perforation, complicating the sialography. she was treated conservatively wi...

Lead is one of the persistent agents found extensively in the environment and has destructive impacts on the tissues. Regarding the high spread of lead, particularly in Iran, we investigated the effects of lead acetate II on the expression level of osteocalcin gene and histological changes of bone. 40 chickens were randomly divided into four groups. As well as the libitum, the control group was...

Background It has been reported that disease activity was correlated to the alterations in vitamin D metabolism and increased bone resorption patients with spondyloarthritis (SpA). Objectives To investigate relationship between turnover markers, Vitamin levels SpA patients. Methods In this cross-sectional study, we included SpA. addition routine blood urine tests, serum 25-(OH)D3, markers (oste...

BACKGROUND Osteocalcin has been reported to be relevant to glucose and lipid metabolism, indicating it may stimulate insulin secretion and improve insulin resistance. Yet the difference between male and female patients is still not clear. We aimed to investigate the difference in serum osteocalcin, and its association with glucose, lipid metabolism, pancreatic function, insulin sensitivity, and...

BACKGROUND AND AIM Recent studies revealed a possible reciprocal relationship between the skeletal system and obesity and lipid metabolism, mediated by osteocalcin, an osteoblast-specific protein. This study aimed to validate the relationship between serum osteocalcin and indices of obesity and lipid parameters in a group of Malaysian men. METHODS A total of 373 men from the Malaysian Aging M...

BACKGROUND Increased iron stores are associated with increased risk of type 2 diabetes, however, the mechanisms underlying these associations are poorly understood. Because a reduction of circulating osteocalcin levels after iron overload have been demonstrated in cell cultures, and osteocalcin is related to glucose and insulin metabolism, the iron-induced osteocalcin reductions could contribut...