The synthesis of imidazolinium salts from the reaction of formamidines and (2-bromoethyl)diphenylsulfonium triflate is described. A variety of symmetrical and unsymmetrical imidazolinium triflate salts were synthesized in high yield in short reaction times under mild conditions. Aromatic and aliphatic N-substituents work well. The reaction is proposed to proceed via generation of a vinyl sulfon...

Starting from the chlorogermyliumylidene chloride salt [L(Cl)Ge:]Cl (1) (L = 1,1'-methylene-3,3'-di-2,6-diisopropyl-phenylimidazole-2,2'-diylidene), the chloride ion can be easily substituted by BPh4 to yield [L(Cl)Ge:]BPh4 (3). Reaction of the latter with NaN3 furnishes [L(N3)Ge:]BPh4 (4). In contrast, the direct reaction of 1 with NaN3 affords exclusively the first azidogermyliumylidene azide...

The treatment in this paper of available quantitative data on the response of taste receptors to sodium salt stimulation clearly indicates that the ions of the chemical stimulus are loosely bound to some substance of the taste receptor. This can be thought of as an initial reaction which ultimately leads to stimulation of the receptor and an eventual depolarization of the associated sensory neu...

The synthesis of 1,4,7-trimethyloxatriquinane (1), a 3-fold tertiary alkyl oxonium salt, is described. Compound 1 is inert to solvolysis with alcohols, even at elevated temperatures, but undergoes facile substitution with the strongly nucleophilic azide anion. Since an S(N)1 pathway is excluded, the only reasonable mechanistic interpretation for the reaction between 1 and N(3)(-) is S(N)2, desp...

An isozyme of malate dehydrogenase (EC 1.1.1.37) from pea seeds has been isolated. The effect of NaCl on the kinetics of the reaction catalyzed by this enzyme has been studied at four pH values, at all of which the results were essentially the same. The activity of the isozyme increases with increasing salt concentrations up to 0.02 M. Higher concentrations are inhibitory. Salt increases the ap...

We have recently synthesized [Ni (MAP) ] complex [H-MAP= 2- (methylamino) pyridine]. 2- (Methy1amino)pyridine reacts with MeLi in THF and generates the lithium salt (Li-MAP). Further reaction of NiCl with two equivalent of this ligand in THF leads to the formation of a dark red solution. Analytical data, molecular weight, and magnetic susceptibility of this complex confirm the formula [N...

An isozyme of malate dehydrogenase (EC 1.1.1.37) from pea seeds has been isolated. The effect of NaCl on the kinetics of the reaction catalyzed by this enzyme has been studied at four pH values, at all of which the results were essentially the same. The activity of the isozyme increases with increasing salt concentrations up to 0.02 M. Higher concentrations are inhibitory. Salt increases the ap...