MOTIVATION Despite RNA-seq reads provide quality scores that represent the probability of calling a correct base, these values are not probabilistically integrated in most alignment algorithms. Based on the quality scores of the reads, we propose to calculate a lower bound of the probability of alignment of any fast alignment algorithm that generates SAM files. This bound is called Fast Bayesia...

Clustering methods unequivocally show considerable influence on many recent algorithms and play an important role in hyperspectral data analysis. Here, we challenge the clustering for mineral identification using two different strategies long wave infrared (LWIR, 7.7–11.8 ?m). For that, compare to perform a unique dataset. The first algorithm uses spectral comparison techniques all pixel-spectr...

Oil spill is one of major marine environmental challenges. The main impacts of this phenomenon are preventing light transmission into the deep water and oxygen absorption, which can disturb the photosynthesis process of water plants. In this research, we utilize SpecTIR airborne sensor data to extract and classify oils spill for the Gulf of Mexico Deepwater Horizon (DWH) happened in 2010. For t...

In bacteria, sulfur metabolism is regulated in part by seven known families of riboswitches that bind S-adenosyl-l-methionine (SAM). Direct binding of SAM to these mRNA regulatory elements governs a downstream secondary structural switch that communicates with the transcriptional and/or translational expression machinery. The most widely distributed SAM-binding riboswitches belong to the SAM cl...

S-adenosylmethionine (SAM), the unique methyl donor in DNA methylation, has been shown to lower lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokine TNF-α and increase the expression of the anti-inflammatory cytokine IL-10 in macrophages. The aim of this study was to assess whether epigenetic mechanisms mediate the anti-inflammatory effects of SAM. Human monocytic THP1 ce...

The Antarctic ice sheet (AIS) is sensitive to short-term extreme meteorological events that can leave long-term impacts on the continent's surface mass balance (SMB). We investigate of atmospheric rivers (ARs) AIS precipitation budget using an AR detection algorithm and a regional climate model (Modèle Atmosphérique Régional) from 1980 2018. While ARs their associated vapor transport are relati...

We present a method of analyzing a set of N time signals fi(t) that consist of local measurements of the same physical observable taken at N sequential locations Zi along the length of an experimental device. The result is an algorithm for reconstructing an approximation F (z, t) of the field f(z, t) in the inaccessible regions between the points of measurement. We also explore the conditions n...

The effects of hypophysectomy and dexamethasone administration on S-adenosylmethionine (SAM) levels in the adrenal, liver, pineal, and various brain regions were examined to determine the central and peripheral relationships between SAM and glucocorticoids in vivo. A simple and sensitive radioenzymatic assay was developed to measure tissue SAM concentrations following removal of its demethylate...

S-adenosyl methionine (SAM) is a ubiquitous methyl donor that was reported to have chemo- protective activity against liver cancer, however the molecular footprint of SAM is unknown. We show here that SAM selectively inhibits growth, transformation and invasiveness of hepatocellular carcinoma cell lines but not normal primary liver cells. Analysis of the transcriptome of SAM treated and untreat...