OBJECTIVE To determine the scoring of Estrogen Receptor (ER) status in carcinoma breast by Allred method that is essentially bimodal and to compare the results with a conventional scoring system. MATERIALS AND METHODS A retrospective, comparative study carried out at Aga Khan University Hospital Section of Histopathology over a period of 18 months, i.e., Jan 2005 to June 2006. Anti ER antibod...

A profile comparison method with position-specific scoring matrix (PSSM) is one of the most accurate alignment methods. Currently, cosine similarity and correlation coefficient are used as scoring functions of dynamic programming to calculate similarity between PSSMs. However, it is unclear that these functions are optimal for profile alignment methods. At least, by definition, these functions ...

There has been no perimetric index or scoring method available to quantify both glaucomatous and neuro-ophthalmic threshold field defects on a continuum, with emphasis on neuronal correlates and presumed damage. The absolute-relative-total scotoma (ARTS) scoring algorithm identifies the percentage of absolute, relative and total scotoma components of static threshold perimetric results. ARTS sc...

Reliable credit scoring models played a very important role of retail banks to evaluate credit applications and it has been widely studied. The main objective of this paper is to build a hybrid credit scoring model using feature selection approach. In this study, we constructed a credit scoring model based on parallel GBM (Gradient Boosted Model), filter and wrapper approaches to evaluate the a...