A leaf spot of figwort (Scrophularia ningpoensis) caused by Phoma sp. Abstract: Since 2006, a new disease caused by Phoma sp. has been identified on figwort (Scrophularia ningpoensis) in Hubei province, China. The pathogen was isolated from diseased S. ningpoensis leaves growing under field conditions, and attempts were made to identify it by cultural and morphological characteristics as well a...

Five iridoid glycosides, including the two new compounds scropolioside-D(2) (1) and harpagoside-B (2), were isolated from the aerial parts of Scrophularia deserti DEL (Scrophulariaceae). Their structures were elucidated on the basis of spectral data to be 6-O-[2",4"-di-O-acetyl-3"-O-trans-cinnamoyl)-alpha-L-rhamnopyranosyl]-8 alpha-hydroxymethyl-1 alpha,5 beta,6 alpha,7 alpha,9 beta-pentahydro-...

BACKGROUND We evaluated the effect of the ethanolic extract of Scrophularia striata on the Iranian strain of Leishmania major (MRHO/IR/75/ER) both in vitro and in vivo conditions. METHODS The effective dose (ED) of ethanolic extract of S. striata were determined using MTT assay on the growth of promastigote forms of L. major in axenic culture media. Then, the ED50 of S. striata on mice perito...

Min-Wook Kim, M.D., Dae-Hyun Jang, M.D., Jun Kang, M.D., Seungok Lee, M.D., Sun Young Joo, M.D., Ja-Hyun Jang, M.D., Eun-Hae Cho, M.D., Young-Chul Choi, M.D., and Jung Hwan Lee, M.D. Departments of Rehabilitation, Hospital Pathology, Laboratory Medicine, and Orthopaedic Surgery, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul; Green Cross Genome, Yongin...

Phenylpropanoid glycoside acteoside was extracted from the traditional Chinese medicine Scrophularia ningpoenis Hemsl. In the present study, we investigated the effects of acteoside administration on serum uric acid levels in mice rendered hyperuricemic with the uricase inhibitor potassium oxonate. When administered orally for 3 days at doses of 50, 100 and 150 mg/kg, acteoside reduced serum ur...

BACKGROUND The cause of death in burn patients after 48 hours of hospitalization has been reported to be bacterial infections. Recently, due to the compounds accelerating the healing process and the intense reduction of treatment side effects, medicinal plants are used to cure burn wound infections. This study aims to investigate the medicinal effect of the ethanolic extract of Scrophularia str...