Nonylphenol (NP), an estrogen like compound classified as an endocrine disrupter capably interfering hormonal system of numerous organisms, originates principally from the degradation of nonylphenol ethoxylates (NE) widely used in industrial, agricultural, commercial and household applications as detergents, emulsifiers, wetting and dispersing agents. Due to the extensive use of NE, NP may reac...

To evaluate whether the sperm DNA fragmentation affects male pronucleus epigenetic factors, semen analysis was performed and DNA fragmentation was assessed by the method of sperm chromatin structure assay (SCSA). Human-mouse interspecies fertilisation was used to create human male pronucleus. Male pronucleus DNA methylation and H4K12 acetylation were evaluated by immunostaining. Results showed ...

BACKGROUND In humans, it is now well documented that rising paternal age is correlated with decreased sperm DNA integrity and embryonic developmental failures. On the other side of the coin, it is also reported that very young fathers such as teenagers carry an increased risk of adverse birth outcomes. These observations suggest that, at least in humans, there is an age window for optimal sperm...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We are delighted to read the insightful commentary by Dr. Evenson (1), a well-known pioneer in the field of SDF testing, in response to the practice recommendations on clinical utility of sperm DNA fragmentation (SDF) testing by Agarwal et al. (2). The process of protamination during spermiogenesis was discovered as e...

Biological samples, including cryopreserved sperm, are routinely X-rayed during air shipment. The goal was to investigate the impact of X-irradiation used for checked and carry-on luggage on bovine sperm chromatin integrity and postfertilization in vitro embryonic development. Frozen domestic bull sperm (Bos taurus) (n=9 bulls) stored in a dry shipper (-160 degrees C) was screened by X-irradiat...

Host stress is well known to result in flare-ups of many bacterial, viral and parasitic infections. The mechanism by which host stress is exploited to increase pathogen loads, is poorly understood. Here we show that Salmonella enterica subspecies enterica serovar Typhimurium employs a dedicated mechanism, driven by the scsA gene, to respond to the host stress hormone cortisol. Through this mech...

In the discipline of civil engineering, foundation plays a crucial role in supporting and containing loads complete structures. Therefore, needs to be strong enough increase any structure's useful life. The soil has direct impact on foundation. Vertisols is with unstable weak that stabilized make suitable for construction purposes. study determine effectiveness pulverized used paper sugarcane s...

In Vitro Fertilization (IVF) is the penetration of ovum cells by spermatozoa in a culture system and reproductive technique that useful for increasing efficiency sperm utilization. vitro fertilization applied to overcome problem infertility prevent birth defects. The success IVF influenced quality spermatozoa. order fulfill this, it necessary select spermatozoa, which separate good from total p...