BACKGROUND Some botanical compounds are considered useful to reduce sebum production. Aim To evaluate the efficacy of a sebum control cream containing polyphenol-rich extract from saw palmetto, sesame seeds, and argan oil in subjects with oily facial skin. METHODS The study was carried out during the winter months (January and February). A total of 20 healthy volunteers (9 male and 11 female,...

The mammalian integument includes sebaceous glands that secrete an oily material onto the skin surface. Sebum production is part of the innate immune system that is protective against pathogenic microbes. Abnormal sebum production and chemical composition are also a clinical symptom of specific skin diseases. Sebum contains a complex mixture of lipids, including triacylglycerides, which is spec...

In many contexts, nutrient excretion by consumers can impact ecosystems by altering the availability of limiting nutrients. Variation in nutrient excretion can be predicted by mass balance models, most of which are premised on two key ideas: (1) consumers maintain fixed whole-body nutrient content (i.e., %N and %P), so-called fixed homeostasis; (2) if dietary nutrients are not matched to whole-...

Purpose: To evaluate the effect of a w/o cream of turmeric (Curcuma longa Zingiberaceae) extract on skin sebum secretion in human volunteers. Methods: Two w/o cream formulations were prepared one contained 5% extract prepared from the rhizomes of the plant, turmeric, and the second was similar except that it did not contain the extract and served as control. The antioxidant activity of the extr...

Measurement of unchanged drug in urine was used to study the rate and extent of amoxycillin absorption after administration of amoxycillin sodium solution to six healthy subjects in a Latin-Square crossover design. The mean (95% CI) fraction of the dose excreted as unchanged amoxycillin decreased (P < 0.05) from 0.50 (0.44-0.56) after 97 mg amoxycillin sodium (= 0.25 mmol amoxycillin) to 0.23 (...

1. Amino acids have been used to test renal reserve filtration capacity. Previous studies suggest that amino acids increase glomerular filtration rate (GFR) by reducing distal tubular flow and tubuloglomerular feedback activity. 2. Glomerular function and the renal tubular handling of sodium during infusion of amino acids was studied in 12 normal volunteers. 3. Clearance of sodium (CNa) was unc...

The object of our investigations has been to study the composition ofsebum and to elucidate its role in maintaining the health of the skin. In a previous paper on the hydrocarbons of sebum (Boughton, Hodgson-Jones, MacKenna, Wheatley & Wormall, 1955) we observed that the squalene content of sebum showed wide variations, both in samples collected from the same subject on different occasions and ...

INTRODUCTION Azelaic acid and mandelic acid are superficial peels commonly applied in people of various age groups. As they are mild and do not cause any side effects, they are also often used in elderly people. AIM To compare the influence of azelaic and mandelic acid peels on facial sebum secretion in mature women aged 49-71 years. MATERIAL AND METHODS The level of secreted sebum was meas...

Sebaceous glands perform complex functions, and they are centrally involved in the pathogenesis of acne vulgaris. Current techniques for studying sebaceous glands are mostly static in nature, whereas the gland's main function-excretion of sebum via the holocrine mechanism-can only be evaluated over time. We present a longitudinal, real-time alternative-the in vivo, label-free imaging of sebaceo...