Hallux rigidus is a progressive disorder of the first MTP joint, characterized by a diminished range of motion (ROM) and degenerative alterations of the joint (1–9). Because some degree of movement is generally available, the term hallux limitus (7) has been used to describe the condition, although the pathologic process is one of progressive degenerative joint disease secondary to biomechanica...

Optimizing perioperative care to provide maximum benefit at minimum cost may be best achieved using a perioperative clinical pathway (PCP). Using our joint replacement surgical home (JSH) model PCP, we examined length of stay (LOS) following total joint arthroplasty (TJA) to evaluate patient care optimization. We reviewed a spectrum of clinical measurements in 190 consecutive patients who under...

Currently, gene finding and RNA secondary structure prediction are performed separately. This is only valid if, for any DNA sequence the location of genes and corresponding RNA secondary structure can assumed to be independent. I develop methods that take a hidden Markov model for gene finding and a stochastic context-free grammar for RNA secondary structure prediction and from these, construct...

Currently, gene finding and RNA secondary structure prediction are performed separately. This is only valid if, for any DNA sequence the location of genes and corresponding RNA secondary structure can assumed to be independent. I develop methods that take a hidden Markov model for gene finding and a stochastic context-free grammar for RNA secondary structure prediction and from these, construct...

Secondary structure in single-stranded DNA impedes the presynaptic association of recA protein and consequently blocks the formation of joint molecules as evidenced by effects of temperature, nucleotide sequence, and ionic conditions. Escherichia coli single-strand-binding protein eliminates sequence-specific "cold spots" by removing folds even from sites of strong secondary structure. Thus, de...