salicylic acid (sa) and methyl jasmonate (meja) as phytohormone regulate synthesis of secondary metabolites in a wide range of plant species by accumulation of phenylalanine ammonia lyase enzyme (pal) and accelerate the production of oxygen free radicals, protein kinase, proline and nitrite oxide content. to study the effect of these compounds on synthesis of secondary metabolites, in two separ...

Background: Sustainable and commercial production of secondary metabolites is a critical issue when dealing with its clinical application. Efforts are still being made to look for biotic or abiotic elicitors with more efficient and universal effects on the improvement of secondary metabolites. Objective: In order to evaluate the suitability of different biotic elicitors on P. harmala L. cell...

After 40 years of intensive research, chemistry of marine natural products has become a mature field. Since 1995, there are signals of decreased interest in the search of new metabolites from traditional sources such as macroalgae and octocorals, and the number of annual reports on marine sponges stabilized. On the contrary, metabolites from microorganisms is a rapidly growing field, due, at le...

Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms, lichen, moss and marine faunas. The structures of the new compounds and details of the source org...

The Miconia genus is the most representative of the Melastomataceae family, and some species are commonly used in Brazilian folk medicine as anti-inflammatory agents. In this work we investigated the leaves from Miconia rubiginosa (Bonpl.) DC, using high-speed countercurrent chromatography, which yielded 11 substances (eight flavonoids, gallic acid, casuarictin, and schizandriside). Identificat...

This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae, published between 1990 and 2014. Iridoids, anthraquinones, triterpenes, indole alkaloids as well as other varying alkaloid subclasses, have s...

Plants are important source for the discovery of new products of medicinal value for drug development and plants secondary metabolites are unique sources for pharmaceuticals food additives, flavors and others industrial values. Commercial importance of these secondary metabolites has resulted in a great interest in its production and in exploring possibilities of enhancing its production by mea...

Fungal kingdom contains many interesting genera that are available around us and can be isolated commonly from different sources. Humicola Nigrospora belonging to class Sordariomycetes, promising fungal produce important secondary metabolites. Hence, this review describes their morphology ecology, highlights on metabolites produced by them, pharmacological activities, as well the biotechnologic...

Melissa officinalis is a plant of Lamiaceae family with medicinal properties which is important for its aromatic, synthetic, and secondary metabolites. The aim of this research was to study the effect of selenium on secondary metabolites and antioxidant properties of Melissa officinalis. For this purpose, an experiment was done in a completely randomized design with four repli...

Teucrium chamaedrys is regarded as an herbaceous perennial plant from Lamiaceae family that is used as medicinal plants and food from ancient times. Due to the recent developments in tissue culture techniques and extraction of secondary metabolites, this study aimed to investigate the explants of the Teucrium for callus induction and secondary metabolites. The interaction of Auxin hormones incl...