Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease that may be associated with other disorders. To date, limited data are available on thyroid dysfunction and SLE in Saudi Arabia. In this retrospective study, we reviewed the cases of 151 patients SLE. The prevalence was 17.2%: 4% hyperthyroid group 11.9% hypothyroid group. Euthyroid sick syndrome found 1.3% patients. Moreover,...

OBJECTIVE To assess the efficacy and safety of subcutaneous (SC) belimumab in patients with systemic lupus erythematosus (SLE). METHODS Patients with moderate-to-severe SLE (score of ≥8 on the Safety of Estrogens in Lupus Erythematosus National Assessment [SELENA] version of the SLE Disease Activity Index [SLEDAI]) were randomized 2:1 to receive weekly SC belimumab 200 mg or placebo by prefil...

The structure of the title compound, C(23)H(21)OPSe(2), consists of fused puckered five- and six-membered rings, PSeC(2)O and C(5)O, respectively, with a C(2)O bridgehead. The C(5)O ring adopts a chair conformation, whilst the C(2)PSeO ring has an envelope conformation.