background: reactive oxygen species (ros)-induced lipidperoxidation can lead to dysfunction of sperm and thereby, infertility may be occurred. so, always there is a balance between amount of ros and anti-oxidant molecules in semen. anti-oxidant enzymes of sperm; superoxide dismutase (sod), glutathione peroxidase (gpx), catalse and zinc and selenium can protect it from destructive effects of ros...

BACKGROUND Older men tend to have poorer semen quality and are generally at higher risks for infertility and abnormal reproductive outcomes. METHODS We employed proton-induced X-ray emission (PIXE, 3 MeV proton beam) to investigate the concentrations of zinc, copper, calcium, sulfur, chlorine, potassium, titanium, iron and nickel in washed sperm and seminal plasma from non-smoking groups of 1...

To investigate the correlations among seminal plasma Magnesium (Mg), Phosphorus (P), Potassium (K), Calcium (Ca), Chromium (Cr), Manganese (Mn), Iron (Fe), Copper (Cu), Zinc (Zn), Selenium (Se), Molybdenum (Mo) and Iodine (I) concentrations and semen parameters [1– 15]. 500 fertile and 1000 infertile males provided a standardized semen specimen. Total Magnesium (Mg), Phosphorus (P), Potassium (...

evidence supports the involvement of nitric oxide (no) in a varity of male reproductive processes such as spermatogenesis, spermiogenesis, sperm motion, sperm metabolism and sperm capacitation. however, low concentration of no is essential in biology and physiology of spermatozoa, but high amounts of no is toxic and has negative effects on sperm functions. on the other hand, it is established t...

Background: Defective sperm function is now recognized as one of the most important causes of male infertility. Lipid peroxidation (LPO) is known to cause various impairments of sperm cells and may play a major role in the etiology of male infertility. Malondialdehyde (MDA) is one of the final products of lipid peroxidation in seminal plasma. Seminal plasma possesses a rich source of different ...

BACKGROUND Many factors may lead to sperm DNA damage. However, it is little known that the correlations of sperm DNA damage with obesity-associated markers, and reproductive hormones and lipids levels in serum and seminal plasma. METHODS In our prospective study, a total of 1 010 subfertile men, aged from 18 to 50 years old, were enrolled from August 2012 through June 2015. Their obesity-asso...

recent studies have reported that metal sulfide nanoparticles had potential adverse effects.  in this research, lead (ii) sulfide nanoparticles have been synthesized under different reaction conditions. scanning electron microscopy and x-ray diffraction were used to characterize the particle size and morphology. distribution, accumulation and toxic effects of nanoparticles on rats as a biologic...

INTRODUCTION An analysis of lead, zinc, cadmium and other trace elements in semen of men from infertile couples was performed to determine the association between abnormal semen parameters and enviromental or occupational exposure to some trace metals. MATERIAL AND METHODS Presence of manganese, cobalt, nickel, copper, zinc, molybdenum, cadmium, tin and lead was measured in seminal plasma of ...

Introduction: Leptin is a critical metabolic signal linking nutrition and reproductive functions. Leptin receptors are expressed in germ cells, Sertoli and Leydig cells. Oxidative stress increases sperm DNA damages. Nitric oxide is a free radical, produced by most cells via Nitric Oxide (NO) synthase and plays stimulatory and inhibitory roles on cells. Physiological concentrations of NO are ess...