We describe here a strategy for photodynamic eradication of solid melanoma tumors that is based on photo-induced vascular destruction. The suggested protocol relies on synchronizing illumination with maximal circulating drug concentration in the tumor vasculature attained within the first minute after administrating the sensitizer. This differs from conventional photodynamic therapy (PDT) of tu...

INTRODUCTION Contact dermatitis is a relatively common dermatosis reported among several population groups from all around the globe. However, the data from Kuwait is unavailable. Patch tests are essential for the diagnosis of contact sensitization. AIM To determine a relative frequency and pattern of sensitizers to different allergens in patients of suspected contact dermatitis in Kuwait and...

It has been increasingly aware to the world today that reserves of fossil fuels are limited and their use has serious environmental side effects. Encouraged by this realization was the evolution of the use of cleaner alternative energy, among which Dye-sensitized solar cells (DSCs) are potentially attractive candidates for the lower cost of producing devices which convert an abundant amount of ...

porphyrins are a ubiquitous large class of naturally occurring macrocyclic compounds with many significant biological representatives comprising heme and chlorophyll. some novel adaptable methods for the synthesis of free-based porphyrins as promising sensitizers for the use in photo-dynamic therapy by the virtue of their known tumor affinity, low dark cytotoxicity, and easy synthesis in good t...

Herein is described a blue-emitting gold( iii )–TADF complex serving as sensitizer for SP-OLEDs, in which an MR-TADF emitter employed the emissive dopant. The SP-OLEDs attained EQE max of up to 16.6%, high color purity and CIE x,y (0.14, 0.18).

In order to support the creation of both artificial living organisms in the USA LANL "Protocell Assembly" project and programmable nano-biorobots in the EU "Programmable Artificial Cell Evolution" project, we used quantum mechanical (QM), density functional theory (DFT), the semiempirical PM3 method, and molecular mechanics (MM) software to investigate various complex photosynthetic systems bas...