background: cadmium (cd) is a heavy metal that has widespread use. it enters the food chain in different ways, including soil and water. cadmium can cause dysfunction of different body organs. zinc (zn) and magnesium (mg) supplementation can have protective effects against cadmium toxicity due to their antagonistic and antioxidants properties. this study examines the influence of supplemental z...

OBJECTIVE Patients with impaired renal function or diabetes are considered to be prone to hyperkalemia. Furthermore, hyperkalemia is an adverse drug reaction of inhibitors of the renin-angiotensin system (RAS) that are established to be efficacious in these patients. However, the current status of hyperkalemia in the clinical setting remains obscure. METHODS A total of 9,117 patients treated ...

results one-, three-, five-, and ten-year graft survival was 93.8%, 86.8%, 76.6%, and 37.4%, respectively. the results of the joint model showed that risk indicators, such as serum creatinine level (p < 0.0001, hr = 1.82), patient’s age (p = 0.006, hr = 1.03), and anti-thymocytes globulin (p = 0.019, hr = 2.57) had a significant relationship to graft survival. conclusions in general, our study ...

between preoperative serum creatinine ≥200 μmol/L group and <200 μmol/L group (p>0.05). CONCLUSIONS: The incidence of ARF after the operation was 9.7%. Preoperative serum creatinine ≥200 μmol/L, hypertension history and extracorporeal circulation duration ≥260 min were independent risk factors of ARF after the operation. The five-year survival rate of ARF after the operation was 56%. The preope...

Immature renal function in neonates requires antibiotic dosage adjustment. Population pharmacokinetic studies were performed to determine the optimal dosage regimens for three types of antibiotics: an aminoglycoside, arbekacin; a glycopeptide, vancomycin; and a carbapenem, panipenem. Eighty-three neonates received arbekacin (n = 41), vancomycin (n = 19), or panipenem (n = 23). The postconceptio...

Background: Cadmium (Cd) is a heavy metal that has widespread use. It enters the food chain in different ways, including soil and water. Cadmium can cause dysfunction of different body organs. Zinc (Zn) and magnesium (Mg) supplementation can have protective effects against cadmium toxicity due to their antagonistic and antioxidants properties. This study examines the influence of supplemental...

In this study we investigated whether a known delta-aminolevulinic acid dehydratase (ALAD) exon 4 polymorphism has a modifying effect on the association of blood or bone lead level with uricemia and indices of renal function among middle-aged and elderly men. We performed a cross-sectional study of subjects who participated between 1991 and 1995 in the Department of Veterans Affairs Normative A...

PURPOSE To evaluate short-term parathyroid hormone (PTH) secretion following total knee arthroplasty (TKA). METHODS 119 Caucasian postmenopausal women aged 49 to 81 (mean, 69.8) years who underwent TKA for end-stage knee osteoarthritis were included. Serum levels of intact-PTH, calcium, phosphorus, and creatinine were evaluated pre- and post-operatively (on days -1 and 7). Creatinine clearanc...

patients and methods this cross-sectional study included a total of 120 adult predialysis ckd patients. forty patients were allocated in each predialysis ckd group of stages 3, 4, and 5. serum ctnt and hs-crp, plasma nt-probnp, and single spot urine albumin creatinine ratio (acr) were measured. ultrasonographic examination of carotid artery was done with 7.5 mhz linear probe in b mode ultrasono...

OBJECTIVE To assess the reversibility of the elevation of serum creatinine levels in patients with diabetes after 5 years of continuous on-trial fenofibrate therapy. RESEARCH DESIGN AND METHODS An on-drug/off-drug ancillary study to the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Lipid Trial to investigate posttrial changes in serum creatinine and cystatin C. Eligible participa...