نتایج جستجو برای: sestrin2
تعداد نتایج: 129 فیلتر نتایج به سال:
Journal:
:Molecular and Cellular Biology
2015
Journal:
:Journal of the American College of Cardiology
2016
Journal:
:Biological and Pharmaceutical Bulletin
2016
Journal:
:Journal of the American College of Cardiology
2018
2015
Hanseong Kim
Sojin An
Seung-Hyun Ro
Filipa Teixeira
Gyeong Jin Park
Cheal Kim
Chun-Seok Cho
Jeong-Sig Kim
Ursula Jakob
Jun Hee Lee
Uhn-Soo Cho
Sestrins are stress-inducible metabolic regulators with two seemingly unrelated but physiologically important functions: reduction of reactive oxygen species (ROS) and inhibition of the mechanistic target of rapamycin complex 1 (mTORC1). How Sestrins fulfil this dual role has remained elusive so far. Here we report the crystal structure of human Sestrin2 (hSesn2), and show that hSesn2 is twofol...
Journal:
:Journal of Biological Chemistry
2020
Journal:
:Frontiers in Immunology
2019
Journal:
:FEBS Journal
2014
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