1 This is a tale of two systems. Both the central nervous system and the immune system are composed of heterogeneous cell populations. Both encompass enormous variability and heterogeneity within each cell type. Both release and respond to neurotransmitters and cytokines. Both sense environmental stimuli. Both respond to deviations in homeostasis. Both use “synapses” for cell–cell interactions....

Serum aminoglutethimide (AG) and N-acetylaminoglutethimide (NAG) concentrations were measured by high pressure liquid chromatography (HPLC) in 24 postmenopausal women with advanced breast cancer receiving increasing doses of oral AG. Patients received 62.5mg b.d., 125mg b.d., 250mg b.d., and 500mg b.d. of AG alone, and 500mg b.d. of AG combined with hydrocortisone (HC) 20mg b.d. Dose was increa...

Our study describes the new seventh edition of the TNM system for lung cancer in a national population and its clinical implications. We classified 1,885 operated patients with lung cancer, reported to the Cancer Registry of Norway (Oslo, Norway) from 2001 to 2005, according to the sixth and the seventh edition of the TNM system. We compared survival differences adjusting for known prognostic f...

In this paper, an improved seventh-order WENO (WENO-Z7) scheme is suggested by extending the 5th-order WENO scheme of Borges et al[R. Borges, M. Carmona, B. Costa, W. S. Don, An improved weighted essentially non-oscillatory scheme for hyperbolic conservation laws, J. Comput. Phys. 227(2008) 3191-3211]. The sufficient condition for seventh-order accuracy is described for the new smoothness indic...

We develop a numerical method for solving the boundary value problem of The Linear Seventh Ordinary Boundary Value Problem by using seventh degree B-Spline function. Formulation is based on particular terms order problem. obtain Septic formulation and Collocation B-spline Method formulated as an approximation solution. apply presented to solve example seventh-order which results show that there...