The effects of different drying methods (freeze drying, vacuum oven drying, and shade drying) on the phytochemical constituents associated with the antioxidant activities of Z. officinale var. rubrum Theilade were evaluated to determine the optimal drying process for these rhizomes. Total flavonoid content (TFC), total phenolic content (TPC), and polyphenol oxidase (PPO) activity were measured ...

Ginger (Zingiber officinale Rosc.) root is known to have anti-oxidative effects. However, studies on the extraction conditions obtain ginger extract (GE) with high antioxidant power not yielded satisfactory results. Therefore, effects of temperature and time GE were investigated. The content 6-gingerol 6-shogaol in was also analyzed. results revealed that carried out at 50°C for 5 h optimal mai...

Ginger is one of the commonly used spices that has been exhibited to have pharmaceutical activities. These therapeutic properties are mainly attribute to gingerols and shogaols. To extract these bioactive compounds, subcritical water extraction (SWE) was employed as a green method. The influence of adding co-solvents, temperature, retention time and particle size on extraction yield were invest...

The rhizome of ginger (Zingiber officinale) is employed in Asian traditional medicine to treat mild forms of rheumatoid arthritis and fever. We have profiled ginger constituents for robust effects on proinflammatory signaling and cytokine expression in a validated assay using human whole blood. Independent of the stimulus used (LPS, PMA, anti-CD28 Ab, anti-CD3 Ab, and thapsigargin), ginger cons...

The extract of ginger (Zingiber officinale Roscoe) and its major pungent components, [6]-shogaol and [6]-gingerol, have been shown to have an anti-proliferative effect on several tumor cell lines. However, the anticancer activity of the ginger extract in pancreatic cancer is poorly understood. Here, we demonstrate that the ethanol-extracted materials of ginger suppressed cell cycle progression ...

BACKGROUND Ginger (Zingiber officinale Rosc.) belongs to the family Zingiberaceae. The health-promoting perspective of ginger is attributed to its rich phytochemistry. This study aimed to review the current evidence on ginger effects as an anti-inflammatory and anti-oxidative. METHODS We searched MEDLINE for related publications using "ginger" and "anti-oxidative" and "ginger" and "anti-infla...