The choroid plexus (CP) is present on the ventricular walls of the brain, produces cerebrospinal fluid (CSF), contains many blood vessels, and is a major functional component of the blood-CSF barrier. The CP is an important site in the pathophysiology of various neurological diseases, including Alzheimer's disease and meningeal amyloidosis. We performed gene silencing in the CP in vivo by using...

OBJECTIVE To document the observations of elementary school teachers (ESTs) in Ilorin, Nigeria on their practice of some types of corporal punishment (CP) that could result in eye injuries among their pupils. MATERIALS AND METHODS A short battery of questions that explored ESTs' observations on attitudes to, and knowledge of some commonly used CP practices was self-administered on 172 consent...

Objectives: Cerebral Palsy (CP) is a non-progressive brain damage that leads to movement and balance disorders. One of the new rehabilitation approaches for such children is Kinesio taping. The present study aimed to investigate the effect of lower limbs kinesio taping on static and dynamic balance in children with CP. Methods: In this pilot randomized clinical trial, 30 children with CP were ...

Short-lived proteins are degraded by proteasome complexes, which contain a proteolytic core particle (CP) but differ in the number of regulatory particles (RPs) and activators. A recently described member of conserved proteasome activators is Blm10. Blm10 contains 32 HEAT-like modules and is structurally related to the nuclear import receptor importin/karyopherin β. In proliferating yeast, RP-C...

Continuous wound infusion (CWI) may protect from inflammation, hyperalgesia and persistent pain. Current local anesthetics display suboptimal pharmacokinetic profile during CWI; chloroprocaine (CP) has ideal characteristics, but has never been tested for CWI. We performed an animal study to investigate the pharmacokinetic profile and anti-inflammatory effect of CP during CWI. A total of 14 pigl...

We consider a model for the decay B 0 → ρ 0 γ in which the short-distance amplitude determined by the Hamiltonian describing b → dγ is combined with a typical long-distance contribution B 0 → D + D − → ρ 0 γ. The latter possesses a significant dynamical phase which induces a CP-violating asymmetry A CP , as well as an important modification of the Stokes vector of the photon.

In this talk we discuss the possibility to measure CP violation in neutrino oscillation experiments using the neutrino beam with energy which is lower (Eν > ∼ 100 MeV) than the one usually considered (typically > 1 GeV) in accelerator experiments. The advantage of using such lower energy neutrino beam is that despite the smaller detection cross sections, the effect of CP violation is larger and...

Recent works on cost based relaxations have improved Constraint Programming (CP) models for the Traveling Salesman Problem (TSP). We provide a short survey over solving asymmetric TSP with CP. Then, we suggest new implied propagators based on general graph properties. We experimentally show that such implied propagators bring robustness to pathological instances and highlight the fact that grap...

SR-2508, a less lipophilic ane neurotoxic analogue of the nitroimidazole, misonidazole, has exhibited significant chemosensitization properties in preclinical studies with alkylating agents. A phase I trial was carried out to assess toxicity and possible pharmacological interactions of the combination of short infusions of SR-2508 and cyclophosphamide (CP). Patients were randomly assigned to re...

In the embryonal carcinoma cell line Tera and its 3.7-fold cis-diamminedichloroplatinum(II) (CDDP)-resistant subline, Tera-CP, parameters were studied that might have changed in relation to induction of CDDP resistance. Phenotypes of both lines were embryonal carcinoma. Karyotypes were related with a decreased mean number of chromosomes and fewer copies of the short arm of chromosome 12 in Tera...