Extracellular matrices (ECM) isolated from chick embryo fibroblast and human and rabbit corneal stromal cells induce polarization and elongation of corneal endothelial cells in culture. ECM isolated from rabbit corneal or bovine aortic endothelial cells neither polarize nor elongate corneal endothelial cells in culture. By indirect immunofluorescence, fibronectin is seen as arrays of long fiber...

Biopersistence of commercial man-made vitreous fibers (MMVF) and crocidolite were studied in Fischer 344 rats. MMVF used were size-selected to be rat-respirable, and rats were exposed nose-only 6 h/day for 5 days to gravimetric concentrations (30 mg/m3) of two fiber glass compositions--a rockwool, and a slagwool--or to 10 mg/m3 of long-fibered crocidolite, or to filtered air. Animals were sacri...

This paper discusses the potential use of multi-walled carbon nanotubes (MWCNTs) to improve the mechanical properties of short glass fiber composites. Two methods to incorporate MWCNTs in short glass fiber composite fabrication were examined. First, Carboxylic-functionalized MWCNTs were dispersed in a silane fiber sizing material and then were allowed to bond to the surface of glass fibers. Sec...

The effect of depolarization on the duration of the action potential was studied in short cardiac Purkinje fibers. Membrane potential was altered by overdriving pacemaker fibers showing spontaneous diastolic depolarization (dog), by injecting constantcurrent pulses through an intracellular microelectrode (sheep), or by voltage clamping (dog). Test action potentials were elicited at the end of 5...

The effect of depolarization on the duration of the action potential was studied in short cardiac Purkinje fibers. Membrane potential was altered by overdriving pacemaker fibers showing spontaneous diastolic depolarization (dog), by injecting constantcurrent pulses through an intracellular microelectrode (sheep), or by voltage clamping (dog). Test action potentials were elicited at the end of 5...

The beneficial effects of carbohydrate-derived fibers are mainly attributed to modulation of the microbiota, increased colonic fermentation, and the production of short-chain fatty acids. We studied the direct immune responses to alimentary fibers in in vitro and in vivo models. Firstly, we evaluated the immunomodulation induced by nine different types of low-digestible fibers on human peripher...