OBJECTIVES/HYPOTHESIS Introduce the Chronic Obstructive Sialadenitis Symptoms (COSS) questionnaire to quantify chronic sialadenitis symptoms and assess the impact of sialendoscopic-assisted salivary duct surgery (SASDS). STUDY DESIGN Retrospective outcome symptoms questionnaire study. METHODS The COSS questionnaire assesses the severity of sialadenitis symptoms from 0 to 100. Patients who u...

OBJECTIVES/HYPOTHESIS To describe the initial results of sialendoscopy as a diagnostic and therapeutic tool in pediatric inflammatory salivary gland disease. STUDY DESIGN Retrospective review of patient medical records from a private practice consisting of three fellowship-trained pediatric otolaryngologists. METHODS Consecutive pediatric patients with either recurrent or chronic sialadenit...

PURPOSE To evaluate the MR appearance of normal and pathologic states of the submandibular gland. METHODS MR images of 22 healthy subjects and 21 patients with histopathologically confirmed disorders of the submandibular gland (five pleomorphic adenomas, two hemangiomas, two malignant lymphomas, one adenoid cystic carcinoma, one squamous cell carcinoma, and 10 cases of sialadenitis) were revi...

Autoimmune lymphocytic infiltration of the salivary glands, termed sialadenitis, is a pathologic feature of Sjögren's syndrome (SjS) that is also prominent in nonobese diabetic (NOD) mice. Genetic factors regulate sialadenitis, and a previous (NOD x NZW)F2 study detected linkage to murine chromosome (Chr) 7. The locus, subsequently annotated as Ssial3, maps to the distal end of Chr7 and overlap...

The development of malignant lymphoma in myoepithelial sialadenitis with and without Sjögren's syndrome was investigated. At first, prelymphomatous proliferation areas showing a polytypic immunoglobulin (Ig) pattern were seen. These transformed into malignant lymphoma with a monotypic Ig pattern, at first in small, circumscribed proliferation areas ("early lymphoma") and later in large, conflue...

Long lasting sialolithiasis can cause structural and functional changes of the salivary glands, inflammatory infiltration and fibrosis. However fat infiltration with sialolithiasis has not been described in the parotid glands. We describe a 60 years old man, bus-driver who presented with a history of reccurent right parotid sialadenitis and was diagnosed to have bilateral sialolithiasis and lef...

BACKGROUND : Either excision of the submandibular gland during neck dissection or having the submandibular gland in radiation field can result in xerostomia, leading to reduced quality of life. The purpose of this study was to evaluate the prevalence of metastasis to the submandibular gland and to identify potential risk factors leading to the presence of metastases into the gland. PATIENTS A...