The filamentous ascomycete Aspergillus nidulans produces three major siderophores: fusigen, triacetylfusarinine C, and ferricrocin. Biosynthesis and uptake of iron from these siderophores, as well as from various heterologous siderophores, is repressed by iron and this regulation is mediated in part by the transcriptional repressor SREA. Recently we have characterized a putative siderophore-tra...

Growth of Legionella species in a defined medium deficient in iron did not result in the production of phenolic or hydroxamate siderophores which could be detected by chemical or biological assay methods. Growth of a variety of other gram-negative organisms under the same conditions resulted in the production of both hydroxamate and phenolate siderophores. The iron-deficient medium limited grow...

Under iron-limited conditions many bacterial species biosynthesize Fe3+ complexing compounds, so-called siderophores. Their most common struc­ tural features are hydroxamate and/or catecholate units, the latter ones mostly derived from 2,3-dihydroxybenzoic acid attached to amino acids, amino alcohols or aliphatic diamines. We wish now to re­ port the isolation and structure elucidation of two c...

Siderophores are chelators synthesized by microbes to sequester iron. This article summarizes the knowledge on the fungal siderophore metabolism with a focus on Aspergillus fumigatus. In recent years, A. fumigatus became a role model for fungal biosynthesis, uptake and degradation of siderophores as well as regulation of siderophore-mediated iron handling and the elucidation of siderophore func...

Iron is essential for nearly all biological events. Siderophores are indispensable for most organisms to obtain iron from iron-limiting milieus. This holds particularly true for pathogens such as the causative agent of tuberculosis - Mycobacterium tuberculosis. The categories of mycobacterial siderophores, their biosynthesis and regulation are summarized here. The siderophore biosynthesis and r...

To guarantee the supply of critical elements in future, development new technologies is essential. Siderophores have high potential recovery and recycling valuable metals due to their metal-chelating properties. Using Chrome azurol S assay, 75 bacterial strains were screened obtain a high-yield siderophore with ability complex metal ions. The production four selected Nocardioides simplex 3E, Ps...

Siderophores are avid ferric ion-chelating molecules that sequester the metal for microbes. Microbes elicit siderophores in numerous and different environments, but the means by which these molecules reenter the carbon and nitrogen cycles is poorly understood. The metabolism of the trihydroxamic acid siderophore deferrioxamine B by a Mesorhizobium loti isolated from soil was investigated. Speci...

Siderophores are iron chelating substances that are also known to bind metals such as Molybdenum and Lead. The pigment produced by P. fluorescens is a siderophore whose ability to bind to different metal ions was investigated in this study. Pigment production was increased in the presence of Sodium, Potassium, Lead, Molybdenum and Cadmium. Siderophores were detected using CAS assay and catechol...