By aiding GPS receiver tracking loops with INS estimates of signal dynamics, GPS/INS ultra-tight coupling can improve the navigation performance in challenging environments. Traditionally the INS data are injected into the loops once every loop update interval, which limits the levels of dynamics accommodated. This paper presents a sample-wise aiding method, which interpolates the aiding Dopple...

A tandem AGV configuration connects all cells of a manufacturing area by means of non-overlapping, sin-gle-vehicle closed loops. Each loop has at least one additional P/D station, provided as an interface between adjacent loops. This study describes the development of three tabu search algorithms for the design of tandem AGV systems. The first algorithm was developed based on the basic definiti...

1 The hard X-ray flux ratio ℜ of the footpoint sources to the loop-top source has been used to investigate non-thermal electron trapping and precipitation in solar flares. Considering the mission-long Yohkoh Hard X–ray Telescope database, from which we selected 117 flares, we investigated a dependence of the ratio ℜ on flare loop parameters like height h and column depth N. We used non-thermal ...

Simple modifications are introduced to the evolvable self-reproducing CA (Evoloop) implemented by Sayama [4] with the aim of mimicking a predator-prey model. A new state to represent the predator (disease) and a corresponding rule set are added to the CA, as well as a memory layer to track predator lifetime. Behaviour of the modified system is investigated and compared for different choices of ...

We have contrived the evoloop 5, 6 , a new selfreproducing loop spontaneously evolving on a simple deterministic 9-state 5-neighbor cellular automata (CA) space. In this article, we examine the evolvability and adaptability of the evoloop through several experiments, the result of which brings us good prospects for the future implementation of an extraordinary large-scale arti cial ecosystem on...

Genomic instability is frequently caused by nucleic acid structures termed R-loops that are formed during transcription. Despite their harmful potential, mechanisms that sense, signal, and suppress these structures remain elusive. Here, we report that oscillations in transcription dynamics are a major sensor of R-loops. We show that pausing of RNA polymerase II (RNA Pol II) initiates a signalin...

1 This paper presents an integrated framework for effective coupling of a signal timing estimation 2 model and Dynamic Traffic Assignment (DTA) in feedback loops. There are many challenges in 3 effectively integrating signal timing tools with DTA software systems, such as data availability, 4 exchange format, and system coupling. In this research, a tight coupling between a DTA model 5 with var...

Insertion and deletion of small heteroduplex loops are common mutations in DNA, but why some loops are prone to mutation and others are efficiently repaired is unknown. Here we report that the mismatch recognition complex, MSH2/MSH3, discriminates between a repair-competent and a repair-resistant loop by sensing the conformational dynamics of their junctions. MSH2/MSH3 binds, bends, and dissoci...

The outer membrane of gram-negative bacteria contains several proteins, and some of these proteins, the porins, have numerous biological functions in the interaction with the host; porins are involved in the activation of signal transduction pathways and, in particular, in the activation of the Raf/MEK1-MEK2/mitogen-activated protein kinase (MAPK) cascade. The P2 porin is the most abundant oute...