A time-interleaved ADC system is an effective way to implement a high-sampling-rate ADC with relatively slow circuits. In the system, several channel ADCs operate at interleaved sampling times as if they were effectively a single ADC operating at a much higher sampling rate. Mismatches among channel ADCs degrade SNR and SFDR of the ADC system as a whole, and the effects of offset, gain and band...

Purpose: The purpose of this study is to compare the diagnostic accuracy of prostate apparent diffusion coefficient (ADC) versus normalized prostate ADC using the normal peripheral zone as the reference site for the differentiation of prostate cancer and prostatitis in the peripheral zone. Methods: Fifty-two patients, 32 with prostate cancer and 19 with prostatitis, were assessed with single-sh...

Here, we extend the L2 ab initio method for molecular photoionization cross-sections introduced in Gokhberg et al. [J. Chem. Phys. 130, 064104 (2009)] and benchmarked in Ruberti et al. [J. Chem. Phys. 139, 144107 (2013)] to the calculation of total photoionization cross-sections of molecules in electronically excited states. The method is based on the ab initio description of molecular electron...

Diffusion-weighted magnetic resonance imaging (DW-MRI) was used to evaluate the effects of single-agent and combination treatment regimens in a spheroid-based animal model of ovarian cancer. Ovarian tumour xenografts grown in non-obese diabetic/severe-combined-immunodeficiency (NOD/SCID) mice were treated with carboplatin or paclitaxel, or combination carboplatin/paclitaxel chemotherapy regimen...

PURPOSE This study quantifies in vivo ischemic stroke brain injuries in rats using ultrahigh-field single-scan MRI methods to assess variations in apparent diffusion coefficients (ADCs). METHODS Magnitude and diffusion-weighted spatiotemporally encoded imaging sequences were implemented on a 21.1 T imaging system, and compared with spin-echo and echo-planar imaging diffusion-weighted imaging ...

In this paper, a comprehensive parametric error model of ultra-wideband analogueto-digital conversion (ADC) is developed, which can likewise be applied for single ultra-fast ADC, multiple concurrent ADC (MC-ADC), time-interleaved ADC (TIADC) and hybrid ADC (H-ADC) as a combination of TIand MC-ADC. The error model comprises quantisation, overflow saturation, DC-offset, gain error, time delay, an...

PURPOSE We aimed to evaluate the apparent diffusion coefficient (ADC) values of metastatic lymph nodes in patients with squamous cell carcinoma (SCC) of the head and neck. METHODS Patients with metastatic lymph nodes underwent 1.5 Tesla diffusion-weighted magnetic resonance imaging (MRI). The ADC values of the histologically proven metastases were evaluated retrospectively and mean ADC values...

BACKGROUND AND PURPOSE Many patients with acute stroke are excluded from receiving thrombolysis agents within the necessary time limit (3 or 6 hours from stroke onset) because they or their family members are unable provide the time of stroke onset. Brain tissue sodium concentration ([Na(+)]) increases gradually and incessantly during the initial hours of experimental focal cerebral ischemia bu...

BACKGROUND AND PURPOSE Previous data have shown the feasibility of identifying ischemic penumbra in patients with acute stroke by using a semiautomated analysis of ADC maps. Here, we investigated whether the fate of ADC-defined penumbra was altered by HG. We also examined the interaction between HG and arterial recanalization on infarct growth. MATERIALS AND METHODS We examined 94 patients by...

OBJECTIVE To evaluate the differences in the apparent diffusion coefficient (ADC) measurements based on three different region of interest (ROI) selection methods, and compare their diagnostic performance in differentiating benign from malignant orbital tumors. MATERIALS AND METHODS Diffusion-weighted imaging data of sixty-four patients with orbital tumors (33 benign and 31 malignant) were re...