Electrode arrays interfacing with peripheral nerves are essential for neuromodulation devices targeting peripheral organs to relieve symptoms. To modulate (i.e., single-unit recording and stimulating) individual peripheral nerve axons remains a technical challenge. Here, we report an in vitro setup to allow simultaneous single-unit recordings from multiple mouse sciatic nerve axons. The sciatic...

This paper describes a detailed protocol for obtaining chronic, multi-site unit recordings in cerebral cortex of awake animals for periods of three months or more. The protocol includes details for making relatively simple and inexpensive implantable multichannel electrodes that consist of arrays of separate microwires. The results reported in this paper suggest that a viable implant will have ...

The majority of techniques for separating multiple single-unit spike trains from a multi-unit recording rely on the assumption that different cells exhibit action potentials having unique amplitudes and waveforms. When this assumption fails, due to the similarity of spike shape among different cells or to the presence of complex spikes with declining intra-burst amplitude, these methods lead to...

The environment recording unit in coral skeletons: structural and chemical evidences of a biochemically driven stepping-growth process in coral fibres J. P. Cuif and Y. Dauphin Université Paris XI-Orsay, Bat. 504, Géologie ,UMR IDES, F-91405 Orsay, France Université Paris VI-UPMC, Micropaléontologie, t. 46–56 E5, 4 place Jussieu, UMR IDESF, F-75252 Paris cedex 05, France Received: 31 August 200...

The inferior colliculus, the primary nucleus in the mammalian auditory midbrain, occupies a central position in the ascending auditory pathway. Nearly all ascending neural pathways converge and synapse in the central nucleus of the inferior colliculus (ICC). Further, the anatomical arrangement of axons and neurons in the ICC suggests the existence of functional regions which may play a role in ...

Submitted to Journal of Neurophysiology 1 Article Type: Innovative Methodology 2 Re-Revised Manuscript (November 29) 3 4 In vivo visualization of single-unit recording sites using 5 MRI-detectable elgiloy deposit marking 6 7 Kenji W. Koyano, Akinori Machino, Masaki Takeda, Teppei Matsui, 8 Ryoko Fujimichi, Yohei Ohashi and Yasushi Miyashita 9 10 1 Department of Physiology, The University of Tok...

By simultaneous recording from neural responses at many different loci at the same time, we can understand the interaction between neurons, and thereby gain insight into the network properties of neural processing, instead of the functioning of individual neurons. Here we will discuss a method for recording in behaving animals that uses chronically implanted micro-electrodes that allow one to t...