BACKGROUND Aloe vera is a natural product that is frequently used in soothing skin care products such as aftersun lotions. In the present study we aimed to explore the anti-inflammatory potential of a highly concentrated A. vera gel in the UV erythema test in vivo. METHODS 40 volunteers with skin types II and III were included in the randomized, double-blind, placebo-controlled, phase III mon...

In the winter of 1959-1960 the number of patients with acute rheumatism who applied to our Centre for treatment was larger than in former years, and most cases presented with a forme fruste of the condition. The three cases reported differed from the others in that they presented with erythema annulare (EA). The chief outward sign of erythema annulare is a series of rings about 2 mm. wide, with...

Disturbances of skin barrier function occur in several skin diseases, e.g., atopic dermatitis (AD), irritant/allergic contact dermatitis (ICD, ACD). Skin barrier damage triggers the production of cytokines that stimulate lipogenesis which may also cause inflammatory processes. The aim of this study was to evaluate the efficacy of a topical skin lipid mixture in the treatment of ICD, ACD and AD....

Erythema Multiforme, (EM) is an uncommon, acute inflammatory disease of the skin and mucous membranes characterized by ulcerations caused by hypersensitivity to drugs, microbial agents or other allergens. An EM outbreak can result in more severe forms of EM involving the skin, and there are several types of EM manifestations. A hemorrhagic crust on the lip is a pathognomonic sign ofthis dis...

BACKGROUND UV radiation induces damage to human skin. Protection of skin by an oral photoprotective agent would have substantial benefits. Objective We investigated the photoprotective effect of oral administration of an extract of the natural antioxidant Polypodium leucotomos (PL). METHODS A total of 9 healthy participants of skin types II to III were exposed to varying doses of artificial U...

Clinical manifestations of sixteen children and teenagers exposed to chemical warfare in Halabje are presented. 15 patients complained of burning of skin. Dry coughing was present in 13 subjects. The most frequent signs were conjunctivitis, skin erythema, edema of the eyelids, hyperpigmentation, ulceration, erosion, dyspnea, closure ofthe eyes, blisters, edema of the skin, and crepitation ...

BACKGROUND Understanding the physiological, chemical, and biophysical characteristics of the skin helps us to arrange a proper approach to the management of skin diseases. OBJECTIVE The aim of this study was to measure 6 biophysical characteristics of normal skin (sebum content, hydration, transepidermal water loss (TEWL), erythema index, melanin index, and elasticity) in a normal population ...

The etiological factors of erythema the face in rosacea are analyzed article. role vasoactive peptides, inflammatory mediators and ticks genus Demodex pathogenesis disease has been determined. main methods treatment considered, including phototherapy with narrowband pulsed radiation platelet autologous plasma (TAP). Current data indicate acceleration natural mechanisms skin regeneration due to ...

The spectrum of skin manifestations of Lyme borreliosis in children is not well characterized. We conducted a retrospective study to analyze the clinical characteristics, seroreactivity to Borrelia burgdorferi sensu lato, and outcome after treatment in 204 children with skin manifestations of Lyme borreliosis seen in 1996-2011. Solitary erythema migrans was the most common manifestation (44.6%)...

Cutaneous lesions are frequent in medium-sized and small vessel systemic vasculitides. The classic cutaneous manifestation of vasculitis is palpable purpura; however the clinical manifestations greatly depend on the size of the vessels affected. They usually do not affect prognosis but relapsing or intractable forms have been described. When skin manifestations are only one of the clinical sign...