Insomnia with objective short sleep duration appears to be a biologically more severe phenotype of the disorder. No longitudinal study to date has examined the association of this type of insomnia with incident hypertension using polysomnography. From a random, general population sample of 1741 adults of the Penn State Cohort, 1395 were followed-up after 7.5 years, and 786 did not have hyperten...

IN THE DECADES FOLLOWING THE FIRST CLINICAL DESCRIPTIONS OF ABNORMALITIES OF BREATHING DURING SLEEP,1-3 medical specialists became progressively more concerned about these disorders. The most widely studied sleep breathing disorders include: obstructive sleep apnea syndrome, central sleep apnea syndrome, Cheyne-Stokes breathing syndrome and sleep hypoventilation syndrome.4 The upper-airway resi...

Prader-Willi syndrome (PWS) is an imprinted genetic disorder conferred by loss of paternal gene expression from chromosome 15q11.2-q13. Individuals with PWS have impairments in ventilatory control and are predisposed toward sleep disordered breathing due to a combination of characteristic craniofacial features, obesity, hypotonia, and hypothalamic dysfunction. Children with PWS progress from fa...

introduction: adenotonsillar hypertrophy (ah) is considered the most common cause of upper respiratory tract obstruction among children. it results in a spectrum of symptoms from mouth breathing, nasal obstruction, hyponasal speech, snoring, and obstructive sleep apnea (osa) to growth failure and cardiovascular morbidity. adenotonsillectomy is a typical strategy for patients with ah, but may le...

This study investigated the prevalence of snoring and symptoms of sleep breathing-related disorders in the multi-ethnic population of Singapore (3 million people, comprising 75% Chinese, 15% Malay and 7% Indian). A multistaged, area cluster, disproportionate stratified, random sampling of adults aged 20-74 yrs was used to obtain a sample of 2,298 subjects (65% response), with approximately equa...