BACKGROUND The aim of this study was to compare the pharmacokinetic properties of sodium ibuprofen and ibuprofen acid incorporating poloxamer with standard ibuprofen acid tablets. METHODS Twenty-two healthy volunteers were enrolled into this randomised, single-dose, 3-way crossover, open-label, single-centre, pharmacokinetic study. After 14 hours' fasting, participants received a single dose ...

A perfusion technique has been used to quantitate the effect of the amino acids glycine and alanine and the dipeptides glycyl-glycine and glycyl-L-alanine on sodium and water absorption from the human jejunum. Although no net absorption of sodium and water was seen in the absence of non-electrolytes, a significant stimulation occurred in the presence of both free amino acids and dipeptides. In ...

OBJECTIVE To determine absorption coefficients for sodium chloride solution (saline) and balanced salt solution at the 193- and 213-nm laser wavelengths. METHODS Absorption coefficients were obtained for each of the component species found in balanced salt solution. This was achieved by measuring laser pulse transmission through solutions of varying concentration. The experiments were repeate...

An absorption process can be carried out to reduce carbon dioxide gas emissions in the surrounding environment. Absorption is a contact between mixture of and liquid that aims remove one components by dissolving it suitable liquid. In this study, CO2 was determine effect flow rate on amount absorbed with NaOH absorbent. The results showed correlation factor inverse because an increase caused de...

Abstract Background and Aims Low sodium intake is associated with a lower blood pressure less proteinuria, which are important therapeutic targets in chronic kidney disease. In contrast, low potassium has been higher incidence of disease cardiovascular events. Counselling patients regarding their requires accurate estimation intake, but 24-hour urinary excretion can deviate substantially from a...

The effect of progressive increases in intraluminal glucose concentration on proximal tubule sodium absorption was studied in normal and streptozotocin diabetic rats by microperfusion. Each tubule was perfused twice, with and without glucose added to the perfusion fluid. Net sodium and water absorption were markedly enhanced by 300-500 mg% intraluminal glucose in both normal and diabetic rats. ...

The present study focused on developing Alkali Activated Fine Aggregate (AAFA) by palletization method. AAFA was manufactured using Ground Granulated Blast Furnace Slag (GGBS) and alkali activator solution at ambient conditions. Sodium hydroxide of six molarity sodium silicate to ratio 2.5 used. AACA's properties are similar Natural except for flakiness elongation index. water absorption Abrasi...

The purpose of this study was to determine the precise role of angiotensin subtype-1 (AT1) and -2 (AT2) receptors and the mechanisms by which they act to alter fluid transport in the rat jejunum. In rats on normal sodium intake, ANG II at low dose stimulated net jejunal fluid absorption, whereas at a high dose the peptide inhibited absorption. Low-dose ANG II-stimulated fluid absorption was blo...

We found mRNA for the three isoforms of the cyclic nucleotide-gated nonselective cation channel expressed in the mucosal layer of the rat intestine from the duodenum to the colon and in intestinal epithelial cell lines in culture. Because these channels are permeable to sodium and calcium and are stimulated by cGMP or cAMP, we measured 8-bromo-cGMP-stimulated sodium-mediated short-circuit curre...

The capacities of 16 proteins, after being subjected to electrophoresis on polyacrylamide gel containing sodium dodecyl sulphate, to bind Coomassie Brilliant Blue G 250 have been measured. It is observed that absorption is a linear function of the surface area of the protein in spherical (globular) configuration. The dye binding capacity of proteins has been used to determine the molar ratio in...