background: a substantial part of the public’s natural radiation dose is due to the inhalation of radon gas. most of the exposure occurs indoors where the airborne concentration of radon and its decay products is usually higher than outdoors. materials and methods: radon activity concentration has been measured twice in 50 classrooms in 5 levels (10 each) during summer and winter using solid-st...

polyamide 6 has been widely used in food packaging applications and also green tea contains amounts of antioxidant compounds. the aim of this study was investigation of green tea effects on properties of polyamide packaging polymer. polyamide 6 was dissolved in methanol which was saturated with calcium chloride. the active packaging film was produced by incorporation of methanol green tea extra...

Pyrrole-imidazole (PI) polyamide is a novel gene regulating agent that competitively inhibits transcription factor binding to the promoter of the specific target gene. Liver fibrosis is an integral stage in the development of chronic liver disease, and transforming growth factor β (TGFβ) is known to play a central role in the progression of this entity. The aim of this study was to evaluate the...

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a membrane protein that can support the binding, internalization, and proteolytic degradation of oxidized low-density lipoprotein. The LOX-1 expression increases in the neointima after balloon injury. To develop an efficient compound to inhibit LOX-1, we designed and synthesized a novel gene silencer pyrrole-imidazole (PI) polya...

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a membrane protein that can support the binding, internalization, and proteolytic degradation of oxidized low-density lipoprotein. The LOX-1 expression increases in the neointima after balloon injury. To develop an efficient compound to inhibit LOX-1, we designed and synthesized a novel gene silencer pyrrole-imidazole (PI) polya...

Pyrrole-imidazole (Py-Im) polyamides are nuclease-resistant novel compounds that inhibit gene expression by binding to the minor groove of DNA. A Py-Im polyamide that targets rat TGF-beta1 was designed as a gene-silencing agent for progressive renal diseases, and the distribution and the effects of this polyamide on renal injury were examined in Dahl-salt sensitive (Dahl-S) rats. For identifica...

caco3 nanoparticles have been synthesized via heat-treatment of a new precursor and solid state reaction. effect of calcinations temperature and quantity of surfactant on particle size has been investigated. the products were characterized by x-ray diffraction (xrd), scanning electron microscopy (sem), transmission electron microscopy (tem) and fourier transform infrared (ft–ir) spectroscopy.

indoor radon and thoron have been measured in the houses ofmoradabad district, uttar pradesh india, by means of solid state nuclear trackdetectors. radon, an invisible radioactive gas, occurs naturally in indooratmospheres and along with thoron is the most important contribution of humanexposure to natural sources. radon exists in soil gas building materials and indooratmosphere to name but a f...

A rapid method for measuring polymerized and depolymerized forms of tubulin in tissues has been developed. The procedure consists of homogenization and centrifugation of the tissue in a microtubule-stabilizing solution and depolymerization of the precipitated microtubules; polymerized and depolymerized forms of tubulin are quantitated by a colchicine-binding assay. The validity of the technique...