The drug making resreach has accentuated on extrusion technology for a long time. The advance of drug bioavailibility, bead manufacturing and granulation is assured by extrusion procedures. There are also diverse effects in resereches with respect to the use of process understanging as a tool in quality management. Many initiatives of FDA such as PAT and QBD are getting accepted. In this survey...

The present work aimed to investigate the impact of critical material attributes on design space production lysozyme pellets with suitable biological and physical properties for subsequent coating process. effect two brands both conformation stabilizing mannitol behavior composition in an extrusion/spheronization process was studied, while experiments were designed according 2 3 factorial desig...

Objective: The objective of the present work was to optimize a rectal suppository containing mucoadhesive pellets Mesalamine achieve local yet sustained release for once-a-day administration therapy Inflammatory Bowel Disease. Methods: Thus, involves forming mesalamine by extrusion spheronization, which were then loaded into be administered rectally. evaluated mucoadhesion strength, swelling po...

Objective: The objective of this investigation was to formulate and evaluate effervescent pellets febuxostat achieve sustain release effect.
 Place Duration Study: APMC College Pharmaceutical education research, Department Pharmaceutics, Himatnagar-383001, between June 2019 July 2021.
 Materials Methods: gastro retentive were formulated using Sodium CMC HPMC K4M HPMCK15M as a polymer....