Spinal cord compression is a major cause of morbidity and or mortality in a cancer patient. This is one of the few oncologic emergencies, as delay in therapy leads to frank paralysis. Several key areas must be considered in the diagnosis and management of spinal cord compression. Because the outcome can be devastating, a diagnosis must be made early and treatment initiated promptly. The purpose...

v Svensk sammanfattning vi Abbreviations viii List of papers ix Thesis at a glance x Introduction 1 Prostate cancer epidemiology 1 Bone metastasis in prostate cancer 3 Metastatic mechanisms 3 Interactions between prostate cancer cells and bone 4 Metastatic spinal cord compression 6 Frequency 6 Localization 6 Pathophysiology 6 Clinical symptoms 8 Diagnosis 9 Prognosis 9 Treatment 10 Spinal cord ...

UNLABELLED Primary bone lymphoma is a rare disease, and the main pathological type is diffuse large B-cell lymphoma. The occurrence of follicular, marginal zone and lymphoplasmacytic lymphomas is rare. Vertebras are also sites that can be affected, and spinal cord compression is reported in 14% of patients with vertebral involvement. However, there is no report on primary vertebral lymphoplasma...

OBJECTIVE To evaluate progression of clinical signs and magnetic resonance imaging (MRI) findings in dogs with cervical spondylomyelopathy (wobbler syndrome) treated medically or surgically. DESIGN Prospective cohort study. ANIMALS 12 Doberman Pinschers. PROCEDURES Neurologic examinations and MRI were performed before medical (n = 9) or surgical treatment (ventral slot, 3) and a minimum o...

A six-year-old Ragdoll cat underwent examination due to a six-month history of slowly progressive gait abnormalities. The cat presented with an ambulatory tetraparesis with a neurological examination indicating a C1-T2 myelopathy. Radiographs of the spine showed a radiopaque irregular line ventrally in the vertebral canal dorsal to vertebral bodies C3-C5. In this area, magnetic resonance imagin...

BACKGROUND Not all patients with spinal cord compression due to cervical spondylotic myelopathy (CSM) have clinical symptoms and signs. The aim of this study was to investigate and compare the imaging findings in asymptomatic and symptomatic patients with CSM with mild to moderate cervical spinal cord compression. MATERIAL AND METHODS A retrospective clinical study included 68 patients. Group A...

Introduction Metastatic spinal cord compression (MSCC) is defined as the compression of the dural sac and its contents by an extradural tumour mass.1 Improved oncological outcomes2 have resulted in more frequent presentation of MSCC.3 Autopsy data demonstrate spinal metastases in 70% of the commonest cancers and an the incidence of symptomatic MSCC in up to 10%.4 Successful treatment achieves m...

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a peripheral nerve disorder probably due to an immunological disturb. It evolves either in a steadily progressive or in a relapsing and fluctuating course. Weakness is mainly in the lower limbs proximally and distally. The electromyography is demyelinating. The cerebral spinal fluid protein is most of times elevated. Sometimes ...

Spinal cord compression caused by cancer metastasis is a medical emergency that should be managed positively. Both multiple myeloma and lung can lead to metastatic deposits in the spinal column induce of cord. However, co-occurring single patient causing are rarely reported literature. We describe case 61-year-old female with whose radiologic characteristics mimicked those cancer. Finally, diag...

This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass.