malignant transformation of ameloblastomas arising from an odontogenic cyst or de novo is wellrecognized. malignancies in ameloblastomas may involve metastasis or a local dysplastic change in the tissue. the latter are classified as ameloblastic carcinomas. a 75-year-old male presented with a mandibular cystic swelling, with no evidence of metastasis. dysplastic ameloblastic cells with spindlec...

Hypotrochoidal profile contours have been produced in industrial applications recent years using two-spindle processes, and they are considered effective high-quality solutions for form-fit shaft hub connections. This study mainly concerns analytical approaches to determine the stresses deformations hypotrochoidal shafts due pure bending loads. The formulation was developed according principles...

To improve the accuracy of thermal characteristics analysis motorized spindle, an online correction model boundary conditions is proposed based on BP neural network (BPNN), experimental data and simulation results are used to construct BPNN correct spindle. Based co-simulation Ansys, Matlab, LabVIEW, a digital twin system for built precisely predict temperature field deformation spindle under v...

pseudotumour is a benign inflammatory lesion. mycobacterial spindle cell pseudotumour (msp) is a rare pseudotumour. it is a benign proliferation of spindle-shaped histiocytes containing acid-fast mycobacterium, commonly reported in immunocompromised patients. msp is usually associated with mycobacterium avium complex (mac). here, we present the case of a 38-year-old gentleman with acquired immu...

Centromeric chromatin, in which centromere protein A (CENP-A) replaces histone H3, is organized during mitosis to form a surface for kinetochore assembly (Palmer et al., 1991; Sullivan et al., 2001; Cleveland et al., 2003). Studies of neocentromeres, which spontaneously form at low frequency on acentric chromosome fragments, have suggested that CENP-A nucleosomes rather than specifi c DNA seque...

Swiss 3T3 fibroblasts and LLC-PK epithelial cells in prometaphase or metaphase were either injected with fura-2 or loaded with the acetoxymethyl ester derivative of fura-2 (fura-2 AM) and monitored by microspectrofluorimetry. With both methods of loading, we observed two aspects of intracellular free calcium (Cai) metabolism. (a) Most fibroblasts and epithelial cells exhibited a gradual rise fr...

Cohesin maintains sister chromatid cohesion until its Rad21/Scc1/Mcd1 is cleaved by separase during anaphase. DNA topoisomerase II (topo II) maintains the proper topology of chromatid DNAs and is essential for chromosome segregation. Here we report direct observations of mitotic progression in individual HeLa cells after functional disruptions of hRad21, NIPBL, a loading factor for hRad21, and ...

*DDA3 Human, mouse Spindle microtubules, midbody Bundles microtubules; regulates the spindle pole localized microtubule depolymerase Kif2a Fidgetin Human, mouse (Fignl1), fl y (Fignl1), worm (FIGL-1), frog (Fignl1) Centrosomes Catalyzes turnover of γ-tubulin; contributes to microtubule depolymeriza-tion and chromosome movement Growing microtubule plus ends Stabilizes microtubule plus ends; infl...

We construct supersymmetric $AdS_5\times \Sigma$ solutions of $D=7$ gauged supergravity, where $\Sigma$ is a two-dimensional orbifold known as spindle. These uplift on $S^4$ to $D=11$ supergravity which have singularites. argue that the are dual $d=4$, $\mathcal{N}=1$ SCFTs arise from $N$ M5-branes wrapped spindle, embedded holomorphic curve inside Calabi-Yau three-fold. In contrast usual topol...

The S. cerevisiae kinesin Kip2 stabilises astral microtubules (MTs) and facilitates spindle positioning through transport of MT-associated proteins, such as the yeast CLIP-170 homologue Bik1, dynein and the adenomatous-polyposis-coli-related protein Kar9 to the plus ends of astral MTs. Here, we show that Kip2 associates with its processivity factor Bim1, the yeast homologue of the plus-end-trac...