A case of systemic mastocytosis is described in which the finding on initial presentation was hepatosplenomegaly. No dermatological abnormality was present, and the bone marrow histology originally caused some confusion with primary myelofibrosis. The clinical course and the importance of distinguishing between these two diseases is discussed. The dermatological manifestation of systemic mastoc...

Multiple myeloma and JAK2 positive chronic myeloproliferative neoplasms are hematologic malignancies with a completely different cellular origin. Two cases of simultaneous occurrence of multiple myeloma, one with primary myelofibrosis and another one with essential thrombocythemia are reported in this article. In such cases, an accurate diagnosis requires a molecular testing, including gene seq...

This study aimed to describe a case in which an isolated splenic metastasis was synchronous with the colonic primary and a concomitant splenic abscess was associated. A wide review of the literature was also performed. A 54-year-old woman with abdominal pain and fever was admitted to our department. Abdominal CT revealed two low-density areas in the spleen and wall-thickening of the left coloni...

Splenosis is the autotransplantation of splenic tissue, mostly found in patient with the history of splenic trauma or splenectomy. Intrahepatic splenosis is exceptionally rare. Thus, it is often clinically misdiagnosed as a malignant tumor. Herein, we present a case of intrahepatic splenosis which was clinically misdiagnosed as a hepatocellular carcinoma in a 50-year-old Chinese male. The patie...

Splenic ectopic pregnancy is very rare, it is easy to be negligence by doctors and the outcome is ominous if not treated promptly. Here we reported an extremely rare case happened in a young Chinese woman. She was admitted in to hospital by hypovolemic shock. A live splenic ectopic pregnancy was diagnosed by ultrasound. Laparotomy with splenectomy was performed and histology confirmed the diagn...