To assess effects of anesthesia and opioids, we studied 13 children with obstructive sleep apnea (OSA, age 4.0 2.2 yr, mean SD) and 24 age matched controls (5.8 4.0 yr). Apnea indices of children with OSA were 29.4 18 hr, median 30 hr. Under inhalational anesthetic, closing pressure at the mask was 2.2 ± 6.9 cmH2O vs -14.7 ± 7.8 cmH2O, OSA vs controls (p<0.001). After intubation, spontaneous ve...

To assess effects of anesthesia and opioids, we studied 13 children with obstructive sleep apnea (OSA, age 4.0 +/- 2.2 yr, mean +/- SD) and 24 age-matched control subjects (5.8 +/- 4.0 yr). Apnea indexes of children with OSA were 29.4 +/- 18 h-1, median 30 h-1. Under inhalational anesthetic, closing pressure at the mask was 2.2 +/- 6.9 vs. -14.7 +/- 7.8 cmH2O, OSA vs. control (P < 0.001). After...

To assess fluid responsiveness in patients under spontaneous breathing activity ventilation remains a challenge for intensive care physicians. Much of the knowledge on heart-lung interactions and dynamic indexes of fluid responsiveness may not be useful for these patients. Historically, the most frequently used variables to guide fluid responsiveness on this population have been the static prel...

purpose: hypercapnia increases minute ventilation (v’e) with little effect on heart rate (hr), whereas hypoxia may increase hr without affecting v’e. however, the effects of hypercapnia and hypoxia on both heart rate variability (hrv) and the clustering of heart beats during spontaneous breathing (respiratory sinus arrhythmia – rsa), are not clear. methods: in this study, 10 human volunteers br...

Coronavirus 2019 (COVID-19) infection has affected the whole world since end of 2019. Patients with disease may present various symptoms and develop associated complications. Spontaneous bilateral pneumothorax pneumomediastinum can also be detected in patients COVID-19 who do not receive positive pressure ventilation support an intense cough. A case spontaneous over course a young male patient ...

We compared high frequency positive pressure ventilation with conventional rate ventilation in 23 preterm infants with the idiopathic respiratory distress syndrome. Nine infants (10 studies) were making spontaneous respiratory efforts during conventional ventilation that abated at 100 breaths per minute. Six of these showed an increase in TcPo2 of at least 10% at the higher rate (mean 18.5%). T...

The effect of low frequency breathing compared with spontaneous breathing was examined at rest and during exercise (40 watts) in 12 patients suffering from severe chronic obstructive bronchitis. At rest low frequency breathing improved significantly the alveolar ventilation and the tensions of oxygen and carbon dioxide in the arterial blood. There was no significant change in ventilation minute...

Background: This study investigated the feasibility of video-assisted thoracic surgery (VATS) performed under two-lung ventilation (TLV) and single-lumen endotracheal tube (SLET) intubation in patients with spontaneous pneumothorax.

In order to evaluate the value of the inspiratory to end-tidal oxygen concentration difference (Io2-E'o2) as a monitor during general anaesthesia, we studied 40 orthopaedic patients allocated randomly to four groups: anaesthesia with enflurane or isoflurane in nitrous oxide with either spontaneous or controlled ventilation. (Io2-E'o2) followed an asymptotically increasing curve because of decre...

Myasthenia gravis (MG) is an autoimmune disease resulting in destruction of the post-synaptic nicotinic receptors at the neuromuscular junction. Classically, the earliest symptoms of MG are ocular, including ptosis and diplopia. Other less common early symptoms include dysphagia and fatigable chewing. Our case report describes the unusual presentation of MG in a teenager patient and presented f...