background: we aimed to value the usefulness of free to total prostate-specific antigen and prostate-specific antigen (psa) density for prostate cancer in the patients with psa levels of 4.0 ng/ml or less. methods: a total of 343 subjects with psa levels of 4.0 ng/ml or less were biopsied. all patients were divided into four groups according to the psa levels: 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, ...

to investigate and compare the infectious and non-infectious complications of single-dose versus multiple-dose antibiotic therapy for trans-rectal ultrasound (trus)-guided biopsy of the prostate. patients were enrolled in a prospective randomized study that was designed to investigate the effects of single-dose versus multiple-dose antimicrobial prophylaxis regimen mainly on asymptomatic bacter...

There are differences between the histopathology of breast cancers in carriers of BRCA1 and BRCA2 mutations. The findings can be interpreted as breast cancer due to BRCA1 has a different natural history from BRCA2 or apparently sporadic disease, which may have implications for screening and management. Mutations in the BRCA1 gene were implicated as causes of different types of cancers including...

ferulago w. koch. (apiaceae) genus is represented by approximately 50 taxa throughout the world. ferulago species are known as “çakşır” or “çağşır” in turkey and mostly known for their aphrodisiac effects. however recent reports emphasize the activity of various ferulago species against cancer, as well. the aim of this study was to investigate the effect of lyophilized extract of f. mughlea peş...

background the most important surgical complications of renal transplantation are stenosis and obstruction of anastomosis of the ureter to the bladder. hence, routine use of ureteral stents to prevent such complications seems logical; however, the optimal time to remove the ureteral stent is still controversial. objectives the purpose of this study was to compare the benefits and complications ...

Background: Prostate cancer is known as one of the most prevalent health disorders in the male population globally. The aim of the current study was to evaluate the effects of separate and concomitant use of MK-2206 and salinomycin on prostate cancer cell line.  Methods: The antitumor potential of separate and concomitant use of MK-2206 and salinomycin was evaluated in a panel of prostate ca...

BACKGROUND Studies have shown that alterations of steroid hormone metabolism, particularly involving testosterone, affect the risk of prostate cancer. Therefore, genetic variation in genes of enzymes which are involved could be of importance. The gene most interest is CYP17, whose enzyme product has an essential role in testosterone hormone synthesis. Some studies have indicated that the A2 all...