INTRODUCTION High quality sputum helps increase the sensitivity of the diagnosis of pulmonary tuberculosis. OBJECTIVES To evaluate the efficiency of the acoustic device (Lung Flute; LF) in sputum induction compared with the conventional method, hypertonic saline inhalation (HSI). METHODS In this crossover study, patients with presumed pulmonary tuberculosis submitted 3 consecutive sputa: th...

OBJECTIVES To describe the early symptoms of pulmonary tuberculosis (TB) when the chest radiograph (CXR) is normal. SETTING Centralized, provincial TB control program. SUBJECTS Twenty-five patients with culture-positive pulmonary TB and a normal CXR were identified from a review of 518 consecutive patients with culture-positive pulmonary TB in the province of Saskatchewan from January 1, 19...

Background: There is growing evidence that diabetes mellitus (DM) is an important risk factor for tuberculosis (TB). A significant number of DM patients have poor glycemic control. This study was carried out to find the impact of poor glycemic control on newly diagnosed smear-positive pulmonary tuberculosis patients with type-2 diabetes mellitus in a tertiary care hospital.Methods: In a hospita...

Sputum smear observation has an important role in tuberculosis (TB) disease diagnosis, because it needs accurate identification to avoid high errors diagnosis. In development countries, sputum smear slide observation is commonly done with conventional light microscope from Ziehl-Neelsen stained tissue and it doesn’t need high cost to maintain the microscope. The clinicians do manual screening p...

OBJECTIVE To identify plasma markers predictive of therapeutic response in patients with multidrug resistant tuberculosis (MDR-TB). METHODS Fifty HIV-negative patients with active pulmonary MDR-TB were analysed for six soluble analytes in plasma at the time of initiating treatment (baseline) and over six months thereafter. Patients were identified as sputum culture positive or negative at bas...

the study was aimed to investigate the diagnostic differences between male and female patients in pulmonary tuberculosis in a tertiary 660 bedded educational respiratory medicine hospital, istanbul, turkey. a retrospective study was conducted with the new diagnosed, 50 men and 50 female pulmonary tuberculous patients. age, symptoms, personal history, radiologic and sputum smear findings were co...

As in other reference centres, the E. Morelli Hospital needs to transfer out all admitted cases to the hospitals referring them for specialised treatment, when culture conversion and clinical stability have been achieved. Patients were transferred out after a median (IQR) hospital stay of 75.5 (51.5–127.5) days; 12 (100%) out of 12 and nine (75%) out of 12 achieved sputum-smear and culture conv...

OBJECTIVE To assess the feasibility of a streamlined strategy for improving tuberculosis (TB) diagnostic evaluation and treatment initiation among patients with presumed TB. DESIGN Single-arm interventional pilot study at five primary care health centers of a streamlined, SIngle-saMPLE (SIMPLE) TB diagnostic evaluation strategy: 1) examination of two smear results from a single spot sputum sp...

OBJECTIVE To determine the incidence of pulmonary tuberculosis (TB) in inmates, factors associated with TB, and the time to sputum smear and culture conversion during TB treatment. METHODS Prospective cohort study. All prisoners with respiratory symptoms (RS) of any duration were evaluated. After participants signed consent forms, we collected three spontaneous sputum samples on consecutive d...

OBJECTIVES To determine whether there are demographic, clinical and radiological differences among patients with pulmonary tuberculosis (TB) and patients with TB and type 2 diabetes mellitus (DM2 + TB). MATERIALS AND METHODS Observational retrospective cohort study. We compared the clinical characteristics of patients according to sex, age, time to sputum conversion to negative, presence of c...