Aim: The objective of this work was to study the effects of formulation variables on the release kinetics of paracetamol tablet formulation. Materials and Methods: Paracetamol tablets were formulated using wet granulation (WG) and direct compression (DC) using two predetermined pressures. Avicel, dicalcium phosphate (DCP) and pregelatinized starch (PGS) were used as directly compressible...

The effects of carbon content on the dynamic and static softening mechanisms of Ti microalloy steels were investigated both in ferrite and austenite regions. &#10The results obtained showed that recrystallization rate decreased as the percentage of carbon content was increased from 0.0035 to 0.110. This is due to the Ti(CN) and TiC precipitates and also the free carbon content. In the ferrite r...

Here we report that the equation of state (EOS) of Mo is obtained by an integrated technique of laser-heated DAC and synchrotron X-ray diffraction. The cold compression and thermal expansion of Mo have been measured up to 80 GPa at 300 K, and 92 GPa at 3470 K, respectively. The P-V-T data have been treated with both thermodynamic and Mie-Grüneisen-Debye methods for the thermal EOS inversion. Th...

We investigate the thermoelastic properties of close-packed phases of iron at pressures up to 400 GPa and temperature to 6000 K using a tight-binding total-energy method and the cell model of the vibrational partition function. The calculated properties are in good agreement with available static and shock-wave experimental measurements. The compressional behavior of a number of thermoelastic p...

Gold nanostructured materials exhibit important size- and shape-dependent properties that enable a wide variety of applications in photocatalysis, nanoelectronics and phototherapy. Here we show the use of superfast dynamic compression to synthesize extended gold nanostructures, such as nanorods, nanowires and nanosheets, with nanosecond coalescence times. Using a pulsed power generator, we ramp...

The yield stress of magnetorheological ͑MR͒ fluids depends on the induced solid structure. Since thick columns have a yield stress much higher than a single-chain structure, we improve the yield stress of MR fluids by changing the fluid microstructure. Immediately after a magnetic field is applied, we compress the MR fluid along the field direction. Scanning electron microscopy images show that p...

Cellular foams used in shoe insoles come in a variety of structural configurations differing with respect to cell geometry. The compression of a cellular foam depends on cell reticulation and size. Examination of the compression behavior of closed cell polyethylene foams revealed distinct time-and nontime-related properties that occur during static and cyclic loading. Physical parameters were d...

Flexible Polyurethane (PU) foam samples with different densities and chemical formulations were tested in quasi-static stress-strain compression tests. The compression tests were performed using the Lloyd LR5K Plus instrument at fixed compression strain rate of 0.033 s-1 and samples were compressed up to 70% compression strains. All foam samples were tested in the foam rise direction and their ...

Films of pulmonary surfactant in the lung are metastable at surface pressures well above the equilibrium spreading pressure of 45 mN/m but commonly collapse at that pressure when compressed in vitro. The studies reported here determined the effect of compression rate on the ability of monolayers containing extracted calf surfactant at 37 degrees C to maintain very high surface pressures on the ...