breast cancer is the most common cancer in women. several risk factors such as age, family history of breast cancer, marital status, early menarche and late menopause are related to breast cancer. obesity is also a main health problem associated with breast cancer incidence and subsequent mortality. association between obesity and expansion of breast cancer may be due to excessive sex steroid h...

Familial adenomatous polyposis (FAP) is an autosomal dominant cancer predisposition syndrome that accounts for approximately 0.5-1% of all colorectal cancer cases. It is caused by germline mutations in the gene encoding the adenomatous polyposis coli (APC) tumor suppressor. Somatic APC inactivation due to mutation or loss of heterozygosity (LOH) promotes the development of adenomatous polyps by...

UNLABELLED Ovarian steroid cell tumors are very rare functioning sex-cord stromal tumors. They comprise <0.1% of all ovarian tumors. Previously designated as lipoid cell tumors, one-third of these tumors are considered malignant with the mean age of presentation at around 40 years. We present a case of a 28-year-old female with 2-year history of hirsutism, virilization, and amenorrhea. She was ...

Objective: The aim of the study is to raise awareness about clinical features,&#x0D; histopathological and radiological analyzes treatment details this rare&#x0D; disease.&#x0D; Methods: A total 55 Langerhans cell histiocytosis patients, diagnosed&#x0D; between years 2006 October 2020 in our department were included the&#x0D; study. patients evaluated terms age, gender, tumor localization,&#x0D...

AIM To confirm the anticancer activity of steroid saponins isolated from the rhizome of Paris polyphylla var. yunnanensis and evaluate the structure-activity relationships of these steroid saponins in vitro and in vivo . MATERIALS AND METHODS Eight known steroid saponins were isolated from the rhizome of Paris polyphylla . The LA795 lung adenocarcinoma cell line from mice was chosen to evalua...

congenital epulis is a very rare benign soft-tissue tumor of uncertain histogenesis, which is also known as “gingival granular cell tumor of the newborn”. it occurs almost exclusively as a single tumor along the alveolar ridge of the maxilla in newborn females. although congenital epulis is strikingly similar to the more common adult granular cell tumor histologically, in contrast to the latter...

granular cell tumor (gct) was first described by abrikossoff in 1926. gct is a rarely seen soft tissue tumor and is generally benign. while the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. gct is rarely seen in the anal-perianal region. in accordance with literature this case was reported because it was thought to ...

intra-abdominal desmoplastic small round cell tumor is a rare entity with a few reports worldwide. this tumor commonly occurs in children and adolescent and occurrence in adult age group is very rare. here, we describe an adult male with symptoms of intestinal obstruction due to abdominal mass, located in splenic flexure. after resection, the diagnosis of intra-abdominal desmoplastic small roun...

background and objectives: giant cell tumor of bone (gct) is often regarded as a benign tumor, but its clinical course is unpredictable, has a high rate of recurrence, and even can metastases and transform to a malignant tumor. histological features of the tumor often could not predict its future biologic behavior, so it is just called ''giant cell tumor'' without indicating malignancy or benig...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 there are a few case series of giant cell tumor (gct) in the spine and sacrum. gct in the thoracic vertebrae is even more exceptional in the medical literature. in this article we report a gct in a 25-year-old male who presented with progressive back pain and dyspnea. on contrast-enhanced multidetector computer tomography,...