The 2014 Indian general election marked a single party – the Bharatiya Janata Party, winning a majority of seats in Lok Sabha, the first time since the 1984 election. The Congress, the other main national party, suffered its worst ever defeat. This election was termed by some as a 'critical election' signalling the advent of a new phase of a ‘BJP dominated’ party system in India. In this paper,...

The 2014 Indian general election marked a single party – the Bharatiya Janata Party, winning a majority of seats in Lok Sabha, the first time since the 1984 election. The Congress, the other main national party, suffered its worst ever defeat. This election was termed by some as a 'critical election' signalling the advent of a new phase of a ‘BJP dominated’ party system in India. In this paper,...

in this article, vibration analysis of an euler-bernoulli beam resting on a pasternak-type foundation is studied. the governing equation is solved by using a spectral finite element model (sfem). the solution involves calculating wave and time responses of the beam. the fast fourier transform function is used for temporal discretization of the governing partial differential equation into a set ...

Articular cartilage is the soft tissue that covers contacting surfaces of bones in synovial joints. Cartilage is composed of chondrocytes and an extracellular matrix containing numerous biopolymers, cations and water. Healthy cartilage functions biomechanically to provide smooth and stable joint movement. Degenerative joint diseases such as osteoarthritis involve cartilage deterioration, result...

Most tissues in the body are under mechanical tension, and while enzymes mediate many cellular and extracellular processes, the effects of mechanical forces on enzyme reactions in the native extracellular matrix (ECM) are not fully understood. We hypothesized that physiological levels of mechanical forces are capable of modifying the activity of collagenase, a key remodeling enzyme of the ECM. ...

Aging is marked by a decline in LV diastolic function, which encompasses abnormalities in diastolic relaxation, chamber filling and/or passive myocardial stiffness. Genetic tractability and short life span make Drosophila melanogaster an ideal organism to study the effects of aging on heart function, including senescent-associated changes in gene expression and in passive myocardial stiffness. ...

OBJECTIVE Chronic kidney disease (CKD) is known to cause significant deterioration in the function of the testicles and sexual dysfunction in male patients who undergo hemodialysis. The aim of this study was to show the changes in the testicles that occur as a result of hypogonadism secondary to CKD and to analyze the elasticity of the parenchyma by shear wave sonoelastography. MATERIALS AND ...

Hypertension and dyslipidemia belong to the most prevalent modifiable risk factors for cerebrovascular and cardiovascular diseases. Hereby, we aimed to examine the combined effects of newly diagnosed hypertension and hyperlipidemia on the characteristics of the arterial wall and on cognitive function. We examined 72 hypertensive and 85 apparently healthy individuals. Based on serum lipid levels...

PURPOSE Bone metastasis invariably increases morbidity and mortality. This study compares the effects of ibandronate and paclitaxel on bone structure and its mechanical properties and biochemical turnover in resorption markers using an immunocompetent Walker 256-Sprague-Dawley model, which was subjected to tumor-induced osteolysis. MATERIALS AND METHODS Seventy rats were divided equally into ...

Does Mental Productivity Decline with Age? Evidence from Chess Players We use data on international chess tournaments to study the relationship between age and mental productivity in a brain-intensive profession. We show that less talented players tend to leave the game in the earliest phases of their career. When the effects of age on productivity vary with unobserved ability, commonly used fi...