the present study assesses the seismic performance of steel moment resisting frames (smfs) retrofitted with different bracing systems. two structural configurations were utilized: ordinary concentrically braces (ocbfs), buckling-restrained braces (brbfs). a 7-story and 18-story steel perimeter smfs were designed with insufficient lateral stiffness to satisfy code drift limitations in high seism...

disposition and transportation of anticancer drugs by human serum albumin (hsa) affects their bioavailability, distribution and elimination. in this study, the interaction of a set of anticancer drugs with hsa was investigated by molecular dynamics and molecular docking simulations. the drugs' activities were analyzed according to their docking scores, binding sites and structural descriptors. ...

Though the application of bimetallic nanoparticles is becoming increasingly important, the local atomistic structure of such alloyed particles, which is critical for tailoring their properties, is not yet very clearly understood. In this work, we present detailed study on the atomistic structure of Au-Cu nanoparticles so as to determine their most stable configurations and the conditions for ob...

density functional theory (dft) based calculations have been performed to examine the relaxations of tautomers of 4–hydroxy–6–methylpyridin–2(1h)–one (mpo), as a representative of pyridinone derivatives, at the fullerene (c60) surfaces. optimized molecular properties including energies, dipole moments and atomic scale quadrupole coupling constants (cq) have been evaluated to investigate the str...

Increasing the population, urbanization has led to the rapid construction of buildings. Due to space constraints and an increase in land cost, these buildings are built too close to each other and can cause damage under dynamic actions such as earthquakes. A new technique, known as Structural coupling, has been developed recently, has found very effective in dissipating the dispersive vibration...

With the advent of the widely heralded "new economy", organizations are undergoing profound changes. The traditional vertically integrated business units seem to serve as the springboard to launch the new organizational forms (e.g., virtual organization, network organization). The basic tenets of the organizational form, viz., strategy, structure and context, have gained renewed vigor as buildi...

The objective of this research is to develop an effective and efficient design methodology for optimizing the configurations of energy dissipation devices (EDD) based on building performance objectives. Current design codes do not provide any guidelines for the optimization of EDD configurations. Previous research efforts are either limited in addressing different performance indices or not eff...

The relative and absolute configurations of naphthomycin A were elucidated by an X-ray structural analysis of a methylation product, 25-O-methylnaphthomycin A iminomethyl ether. The absolute configuration was confirmed by degradation (O3, NaBH4) to (S)-butane-1,2,4-triol.

The effect of solvent on the configurational characteristics of the polymeric chain is studied for the poly@-chlorostyrene)-benzene system. Among all possible configurations of benzene around the chain unit, two configurations, referred to as the parallel and perpendicular configurations, are found to lead to the lowest energy of interaction. The potential prevailing at the parallel configurati...

Using density-functional theory, we predict stable alloy configurations (ground states) for a 1 nm Pt-Pd cuboctahedral nanoparticle across the entire composition range and demonstrate their use as tunable alloy catalysts via hydrogen-adsorption studies. Unlike previous works, we use simulated annealing with a cluster expansion Hamiltonian to perform a rapid and comprehensive search that encompa...