Cutaneous lupus erythematosus (CLE) encompasses a wide range of dermatologic manifestations, which may or may not be associated with the development of systemic disease. Cutaneous lupus is divided into several sub-types, including acute CLE (ACLE), sub-acute CLE (SCLE) and chronic CLE (CCLE). CCLE includes discoid lupus erythematosus (DLE), LE profundus (LEP), chilblain cutaneous lupus and lupu...

BACKGROUND The purpose of this study was to evaluate the complications of a sub-Tenon injection of triamcinolone acetonide in patients with uveitis. METHODS We retrospectively reviewed the records of uveitis cases treated from 1999 to 2003 in Kaohsiung Chang Gung Memorial Hospital. Thirty patients (45 eyes), who received a sub-Tenon injection of 0.5 ml of a triamcinolone acetonide suspension ...

Anal fissure is an ischemic ulcer that occurs in anoderm and it has no obvious etiology and pathophysiology in current medicine. Anal fissure has a profound history in Persian and Persian medicine and wallflower (Erysimum cheiri (L.) Crantz) has been a common medication in this case. Traditional oil and/or dilute decoction of wallflower has been introduced as an effective topical medic...

Background: The expression ‘topical fluoride treatment’ refers to methods that provide a high concentration of exposed tooth surfaces for local protective effect. most popular topical agents are toothpastes (dentifrices), mouthrinses, gels and varnishes contain fluoride. These may be used separately or in combination. Topical application will simple but important procedure is nominated by denta...

Considering convergent product as an important manufacturing technology for digital products, we integrate functions and sub-functions using a comprehensive fuzzy mathematical optimization process. To form the convergent product, a web-based fuzzy network is considered in which a collection of base functions and sub-functions configure the nodes and each arc in the network is to be a link betwe...

describing drug disposition in eye compartments to simulate disposition of clonidine after topical (eye drop) administration [1]. This example extends the methodology to describe the disposition of timolol in different eye tissues and plasma after topical administration. Timolol is a nonselective beta-adrenoceptor antagonist used to lower intraocular pressure (IOP) [2]. A serious disadvantage o...

Most stochastic gradient descent algorithms can optimize neural networks that are sub-differentiable in their parameters; however, this implies the network’s activation function must exhibit a degree of continuity which limits network model’s uniform approximation capacity to continuous functions. This paper focuses on case where discontinuities arise from distinct sub-patterns, each defined di...