An unmarried woman of 21 developed diabetes mellitus in 1957 when aged 12. Her subsequent management was often complicated by diabetic ketoacidosis and coma, eventually traced to failure to administer her insulin correctly. At a number of centres in the London area she received psychiatric treatment, with a diagnosis of inadequate immature personality and psychopathic features. In 1962, at the ...

Deliberate injection of mercury, especially subcutaneous injection, is rare but is seen in psychiatric patients, individuals who attempt suicide, those who are accidentally injected, and boxers who wish to build muscle bulk. Metallic mercury plays a major role in ethnic folk medicine. Neurologic and renal complications can result from high systemic levels of mercury, and subcutaneous injection ...

Preperitoneal hematomas are rare and can develop after surgery or trauma. A 74-year-old woman, receiving systemic anticoagulation, developed a massive preperitoneal hematoma after a subcutaneous injection of teriparatide using a 32-gauge, 4 mm needle. In this patient, there were two factors, the subcutaneous injection of teriparatide and systemic anticoagulation, associated with development of ...

BACKGROUND Injection site reactions are well recognized in patients treated with etanercept. Previous reports describe histologic findings of a cell-mediated T(H)1 reaction, with CD8+ T cells composing the majority of the dermal infiltrate. OBSERVATIONS A pruritic, erythematous, edematous patch occurred on the right thigh of a 57-year-old white woman treated for rheumatoid arthritis within 12...

Gramoxone is a commercial formulation of a herbicide containing the di-metho sulphate salt of paraquat (1,1'-dimethyl-4, 4'-dipyridilium). Bullivant (1966) reported that up to July 1964 one case of paraquat poisoning had occurred in a child in Ireland. He described two additional cases in men in 1966. The first was that of a 28-year-old man who drank half a glass of 20% paraquat solution; a day...

Currently, intraperitoneal (IP) injection of D-luciferin is the preferred method of providing substrate for bioluminescent imaging (BLI); however it has a failure rate of 3-10% due to accidental intestinal injection. The present study evaluates the quality of BLI after subcutaneous (SC) injection of D-luciferin and demonstrates the effectiveness of SC injection in anatomically disparate tumor m...

MM et al. Toxicity of sunitinib plus bevacizumab in renal cell carcinoma. Renal thrombotic micro-angiopathy caused by anti VEGF-antibody treatment for metastatic renal-cell carcinoma. A, Nadasdy T et al. Proteinuria in a patient receiving anti-VEGF therapy for metastatic renal cell carcinoma. Haemorrhagic shock induced by subcutaneous insulin injection Sir—A number of chronic kidney disease pat...

Following silicone injection, end organ toxicity can occur. To our knowledge this report documents the first case of silicone embolization in the Caribbean and serves to highlight an emergent danger associated with its illicit use for cosmetic purposes in this region.

The aim of this study was to investigate the anesthetic effect and risk of epinephrine for subcutaneous single injection digital block. Either 3.0 mL 1.0% Lidocaine or a 3.0 mL 1.0% Lidocaine with (1 : 100,000) epinephrine was injected into the subcutaneous space at the middle point of the palmar digital crease of the 18 middle fingers of 9 healthy volunteers. The SpO(2) of the fingers decrease...