Since Crohn's disease is a transmural disease, we hypothesized that examination of deep submucosal tissues directly involved in the inflammatory disease process may provide unique insights into bacterial populations transgressing intestinal barriers and bacterial populations more representative of the causes and agents of the disease. We performed deep 16s microbiota sequencing on isolated ilea...

OBJECTIVES/HYPOTHESIS To study differences in inferior nasal turbinate (INT) mucosal and submucosal wound-healing histology after radiofrequency tissue ablation (RTA) and monopolar electrocautery (MEC). STUDY DESIGN Randomized controlled trial. METHODS Experimental study in sheep. Using hematoxylin- and eosin-stained sections, stromal fibrosis, submucosal interstitial space volume (ISV), mu...

Background: Tracheobronchopathia Osteochondroplastica (TO) is a benign disease of low incidence that characterized by multiple submucosal cartilaginous and bony tracheobronchial nodules

i ntroduction: our study was designed to assess the effect of the submucosal injection of dexamethasone on postoperative discomfort after surgical removal of impacted mandibular third molars. m at erials and methods : twenty six patients with bilaterally bony impacted mandibular third molars were recruited to this split mouth study. on the study side, prior to surgery, 8 mg of dexamethasone was...

benign tumors [1]. Esophagectomy is the conventional surgical approach to treatment, but recently less invasive approaches by endoscopic therapy have become more widely used [2,3]. However, because conventional endoscopic therapy cannot obtain specimens for pathological examination and is associated with a risk of residual or recurrent hemangioma [4], en bloc removal is another possible treatme...

In the past 130 years, many surgical procedures for turbinate reduction have been developed. We analyzed the long-term efficacy of 6 of these surgical techniques (turbinectomy, laser cautery, electrocautery, cryotherapy, submucosal resection, and submucosal resection with lateral displacement) over a 6-year follow-up period. We randomly divided 382 patients into 6 therapeutic groups and surgica...

lipomas of the gasterointestinal tract are relatively uncommon in clinical practice. most cases are asymptomatic with small tumor size and do not need any special treatment but the large ones are known to cause symptoms such as abdominal pain, obstruction, intussusceptions, and bleeding. the majority (90%) of these lesions are submucosal with predominantly right sided with a slight preponderanc...

Submucosal chromoendoscopy involves the injection of a solution containing a vital stain, usually indigo carmine, into the intestinal wall submucosal layer. This allows to: Better delimit and characterize the various epithelia present (colonic mucosa, adenoma, hyperplastic polyp, serrated polyp, small bowel mucosa); expose and delimit lesion implantation areas; cooperate in the lifting of resec...

Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is performed to obtain specimens for pathological analysis. For this procedure, 19-gauge (19G), 22-guage (22G), and 25-guage (25G) needles are available. The needles are classified into aspiration type and biopsy type. A 56-year-old woman underwent upper gastrointestinal endoscopy that showed a 38-mm-diameter submucosal tumor. The el...

has recently been developed for endo− scopic treatment of gastrointestinal tu− mors, enabling en bloc resection of even large tumors [1,2]. Although many en− doscopists now perform ESD for early− stage gastric cancer, ESD has yet to be es− tablished as a safe therapy for colonic dis− eases, even in Japan. It is still unclear whether ESD is indicated for submucosal tumors (SMTs), and ESD for col...