background: the value of serial measurement of serum ß subunit of human chorionic gonadotropin (ßhcg) and ultrasonography in the early diagnosis of ectopic pregnancy has well established. objective: the objective of this study was to explore the diagnostic value of raising level of serum ßhcg, single measurement of progesterone (p) and estradiol (e2) in early diagnosis of ectopic pregnancy. mat...

Benzodiazepines (BDZ) are widely used in clinics the treatment of psychiatric disorders, and their main action is considered to be determined by more selective binding with ?1, ?2, ?3 or ?5 subunits GABA receptor.
 The aim this work was studying molecular mechanism new analgesic – propoxazepam its metabolite (3-hydroxypropoxazepam) on ?3, ?4 containing GABAA channels.
 Materials metho...

BACKGROUND Cockroaches are serious urban pests that can transfer disease-causing microorganisms as well trigger allergic reactions and asthma. They commonly managed by pesticides act on cys-loop ligand-gated ion channels (cysLGIC). To provide further information will enhance our understanding of how insecticides their molecular targets in cockroaches, we used genome reverse transcriptase polyme...

We explore tautomerism and its consequences in the first example of diamino-benzoquinonediimine bearing both electron-donating electron-withdrawing groups on same 6-? electron subunit.

Background: Rotaviruses (RV) are important viral diarrheal agents in calves. Vaccination is an optimum measure to prevent bovine rotaviruses (BRV) infection. However, little research on BRV VP7 vaccine has been done and currently there is no BRV vaccine. Objective: To prepare a subunit vaccine of BRV and investigate its efficacy. Methods: Total RNA was extracted from MA104 cells infected with b...

Background: Breast cancer is known as the most widely recognized dangerous tumors; therefore, the most common reason for mortality among all instances of harmful neoplastic illness in females. This is because the lack of specific signs and symptoms at the early stage and at the aggressive nature. Currently, breast cancer treatment such as chemotherapy, surgery and radiotherapy has not been effe...

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a potentially fatal autoimmune syndrome in which IgG antibodies target the NR1 subunit of NMDA resulting profound dysregulation and neurotransmission.