Whilst preparing a pilot survey in the North Midlands (Sheffield) Faculty to study the position in regard to the treatment of acute tonsillitis, I had occasion to write to some of the ear, nose, throat and paediatric consultants in the faculty to ask for their views. In many instances their replies were extremely helpful, though somewhat conflicting, and this has led me to a further study of th...

Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens. One hundred and nine patients with genital ulcers (75 men and 34 women) seen at the Special Treatment Clinic in Nairobi, Kenya, were randomly assigned to treatment with a seven day course of either s...

Veterinary and human medicines containing a sulphonamide are used to prevent infections in a variety of situations. For sulphonamide products that contain many components (e.g. four or more sulphonamides) chromatographic techniques are recommended [l-5]. However, for products formulated to contain a sulphonamide and another drug which increases the activity of the sulphonamide, simple, rapid an...

so than in the past. In 1959, with an incidence of 6.68 cases per thousand in the Royal Air Force abroad (Air Ministry, 1961), it was the commonest cause of admission to hospital after excluding injuries, acute upper respiratory disease, skin diseases, and non-specific gastroenteritis. In the United Kingdom notifications have risen over the past 20 years, especially in regard to dysentery cause...

OF THE THESIS Synthesis, Characterization and Biological Activities Of Novel Hybrid Molecules Related to Substituted Hydrazones, Sulphonamides and Sulphonates of NonSteroidal Anti-Inflammatory Drugs CHAPTER 1 A Brief Overview of Synthesis and Pharmacological Activities of Substituted Hydrazones, Sulphonates and Sulphonamides This chapter deals with general survey of the literature related to th...

Although lymphogranuloma venereum (LGV) is a serious problem in many foreign countries, it is comparatively rare in the United Kingdom. As shown by Alergant (1957), "Somewhere between a quarter and a third of all cases of LGV reported in Great Britain are first seen"-at the Seamen's Dispensary, Liverpool. A few additional cases are treated in the other regional clinics, notably at Birkenhead, w...

capacity to synthesize a large amount of s01I\ essential vitamins which are absorbed a.nutilized by the host animal and that bacterio~ static agents like sulphonamides can effectively inhibit this intestinal synthesis of the vitaminsWith these drugs as new tools and with improve technique of estimation, it has been shown Wf some nutrition experts and bacteriologists tha rats can synthesize some...