Zusammenfassung Die Erstellung eines individuellen Programms aus einer Softwareproduktlinie (Programmfamilie) erfordert auf Anwendungsund Datenbankseite einen speziell angepassten und aufeinander abgestimmten Funktionsumfang. Die Modellierung maßgeschneiderter Relationenschemata stellt z.B. aufgrund der großen Anzahl an Programmen, die aus einer Produktlinie erstellt werden können, eine Herausf...

Purpose: Superimposition of two dimensional preoperative and postoperative facial images, including radiographs and photographs, are used to evaluate the surgical changes after orthognathic surgery. Recently, three dimensional (3D) imaging has been introduced allowing more accurate analysis of surgical changes. Surface based registration and voxel based registration are commonly used methods fo...

One of the most important tasks in forensic anthropology is human identification. Over the past decades, forensic anthropologists have focused on improving techniques to increase the accuracy of identification. Following a thorough examination of unidentified human remains, the investigator chooses a specific identification technique to be applied, depending on the availability of ante mortem a...

Three experiments tested whether the scalar property of timing could occur when humans timed short durations under conditions in which it was unlikely that they developed reference memories of temporal "standards". Experiment 1 used an episodic version of a temporal generalization task where judgements were made of the potential equality of two durations presented on each trial. Unknown to the ...

A novel self-organizing algorithm for conformational sampling is introduced, in which precomputed conformations of rigid fragments are used as templates to enforce the desired geometry. Starting from completely random coordinates, the algorithm repeatedly superimposes the templates to adjust the positions of the atoms, thereby gradually refining the conformation of the molecule. Combined with p...

The ever growing size and complexity of software systems is making it increasingly harder to built systems that both meet current and future requirements. During architecture design, a lot of important design decisions are taken. In this paper, we present an architecture design notation based on UML's activity diagrams. The notation allows for the specification of architecture fragments and sup...

Low renal nitric oxide (NO) bioavailability contributes to the development and maintenance of chronic hypertension. We investigated whether impaired l-arginine transport contributes to low renal NO bioavailability in hypertension. Responses of renal medullary perfusion and NO concentration to renal arterial infusions of the l-arginine transport inhibitor l-lysine (10 μmol·kg(-1)·min(-1); 30 min...

MOTIVATION The primary function of DNA is to carry genetic information through the genetic code. DNA, however, contains a variety of other signals related, for instance, to reading frame, codon bias, pairwise codon bias, splice sites and transcription regulation, nucleosome positioning and DNA structure. Here we study the relationship between the genetic code and DNA structure and address two q...