The stepwise mutation model (SMM) is a simple, widely used model to describe the evolutionary behaviour of microsatellites. We apply a Markov chain description of the SMM and derive the marginal and joint properties of this process. In addition to the standard SMM, we also consider the normalised allele process. In contrast to the standard process, the normalised process converges to a stationa...

The development of a Shared Mental Model (SMM) between team members and effective communication of the shared knowledge have been found to improve teamwork performance. In human-IVA heterogeneous teams, the communication required to develop a SMM is difficult as each party belongs to different worlds (i.e. real and virtual). Moreover, humans may differ in how they produce and perceive communica...

Social psychology research on teams has shown that team performance improves when team members have a so-called shared mental model (SMM). We observe that a decision support system (DSS) and its user can be viewed as a team whose task is to make a (good) decision. Therefore we argue that it is important for good user-DSS team performance that they have a SMM. In this paper we make precise what ...

Smooth muscle myosin (SMM) light chain kinase (MLCK) phosphorylates SMM, thereby activating the ATPase activity required for muscle contraction. The abundance of active MLCK, which is tightly associated with the contractile apparatus, is low relative to that of SMM. SMM phosphorylation is rapid despite the low ratio of MLCK to SMM, raising the question of how one MLCK rapidly phosphorylates man...

A series of 2,2'-bipyrimidine-bridged dinuclear lanthanide complexes with the general formula [Ln(tmhd)3]2bpm (tmhd = 2,2,6,6-tetramethyl-3,5-heptanedionate, bpm = 2,2'-bipyrimidine, Ln = Gd(III), 1; Tb(III), 2; Dy(III), 3; Ho(III), 4 and Er(III), 5) has been synthesized and characterized. Sublimation of [Tb(tmhd)3]2bpm onto a Au(111) surface leads to the formation of a homogeneous film with he...

In this paper, we present a formal model, named PobSAM (Policy-based Self-Adaptive Model), for modeling self-adaptive systems. In this model, policies are used as a mechanism to direct and adapt the behavior of self-adaptive systems. A PobSAM model consists of a set of self-managed modules(SMM). An SMM is a collection of autonomous managers and managed actors. Managed actors are dedicated to fu...

Single-molecule magnet (SMM) properties of crystals of a terbium(III)-phthalocyaninato double-decker complex with different molecular packings (1: TbPc₂, 2: TbPc₂·CH₂Cl₂) were studied to elucidate the relationship between the molecular packing and SMM properties. From single crystal X-ray analyses, the high symmetry of the coordination environment of 2 suggested that the SMM properties were imp...

Cannabinoid receptor 2 agonists and inverse agonists are emerging as new therapeutic options for a spectrum of autoimmune-related disease. Of particular interest, is the ability of CB2 ligands to regulate microglia function in neurodegenerative diseases and traumatic brain injury. We have previously reported the receptor affinity of 3',5'-dichloro-2,6-dihydroxy-biphenyl-4-yl)-phenyl-methanone (...

Social media has become a major channel for firms’ marketing communications. Yet studies on the impact of social media marketing (SMM) have been limited to a few large firms. Motivated by the lack of understanding of the effectiveness of SMM for small and medium-sized enterprises (SMEs), this study investigates the impact of online SMEs’ SMM messages on their sales performance through customer ...

Özetçe —Bu çalışmada, Saklı Markov Modeli (SMM) olarak modellenen zaman serilerinin topaklandırılması için yeni bir yöntem önerilmektedir. Topaklardaki SMM parametrelerinin güncellenmesi için son yıllarda yapay öğrenme literatüründe popüler olmaya başlayan saklı değişken modelleri için spektral öğrenme yöntemleri kullanılmaktadır. Spektral yöntemler, alışılagelmiş beklenti-enbüyütme yaklaşımını...