Serotonin (5-hydroxytryptamine) is a biogenic amine that acts as a neurotransmitter in the central and peripheral nervous systems [1]. It is present in a variety of organisms, ranging from humans to species such as worms that have primitive nervous systems [2], and mediates a variety of physiological responses in distinct cell types. It is believed to play a role in the regulation of various co...

Nanostructured bupivacaine-selective molecularly imprinted 3-aminophenylboronic acid-p-phenylenediamine co-polymer (MIP) films have been prepared on gold-coated quartz (Au/quartz) resonators by electrochemical synthesis under cyclic voltammetric conditions in a liquid crystalline (LC) medium (triton X-100/water). Films prepared in water and in the absence of template were used for control studi...

The cover image is based on the Short Communication Determination of aflatoxin B1 by biomass derived porous carbon modified electrode with molecularly imprinted polymer Longyi Chen et al., DOI: 10.1002/elan.202200371.

Molecularly imprinted polymer (MIP) may not selectively recognize small template of limited number of functional groups, such as 2-chlorophenol (2-CP). In this work, a novel method was proposed to improve the recognition ability of the molecularly imprinted solid phase extraction (MISPE) of 2-CP from environmental waters. This was achieved by derivatization of 2-CP with 4-amino-anti-pyrine (4-A...

We report the synthesis of small (below 100 nm), stable and water-compatible superparamagnetic molecularly imprinted nanocomposites using water-soluble, dithiocarbamate-based photoiniferters. These agents were adsorbed directly on surface maghemite nanoparticles allowed thin layers polymer able to specifically selectively bind green fluorescent protein as a model protein. To best or our knowled...

The synthesis of core-shell molecularly imprinted polymer nanoparticles (MIP NPs) has been performed using a novel solid-phase approach on immobilised templates. The same solid phase also acts as a protective functionality for high affinity binding sites during subsequent derivatisation/shell formation. This procedure allows for the rapid synthesis, controlled separation and purification of hig...

A signalling molecularly imprinted polymer was synthesised for easy detection of tamoxifen and its metabolites. 6-Vinylcoumarin-4-carboxylic acid (VCC) was synthesised from 4-bromophenol to give a fluorescent monomer, designed to switch off upon binding of tamoxifen. Clomiphene, a chlorinated analogue, was used as the template for the imprinting, and its ability to quench the coumarin fluoresce...

The present study reports the fabrication of mesoporous-structured ratiometric molecularly imprinted sensors using a combined surface-imprinted and ratiometric fluorescence method. The sensors were subsequently examined in the selective and sensitive determination of 2,4,6-trinitrophenol (TNP). In the preparation of the ratiometric system, the reference dye CdTe quantum dots were embedded in si...

A glassy carbon electrode modified with a molecularly imprinted polymer (MIP) containing phenacetin recognition sites is introduced. The phenacetin-selective MIP was synthesised based on the electropolymerisation of pyrrole in a 1:1 (v/v) water/ethanol with HClO4 solution. The MIP-modified electrode showed higher recognition ability in comparison with a bare electrode for procaine and aminopyri...

This article reviews the recent developments in Bio-Analytical sample preparation techniques and gives an update on basic principles, Applications and comparative discussion on the advantages and limitations of each technique. Conventional Solid-Phase Extraction (SPE), Molecularly Imprinted Polymer SPE techniques are have been considered as methods of past. Developments in SPE techniques such a...